Literature DB >> 26543802

Cost-Effectiveness of Radiofrequency Ablation for Supraventricular Tachycardia in Guatemala: Patient outcomes and economic analysis from a low-middle-income country.

Benjamin Cruz Rodriguez1, Sergio Leal2, Gonzalo Calvimontes2, David Hutton3.   

Abstract

BACKGROUND: Radiofrequency ablation (RFA) is an established but expensive treatment alternative for many forms supraventricular tachycardia (SVT). Currently no studies exist on the cost-effectiveness of RFA compared to medical treatment (MT) in adult Latin American population.
METHODS: Between 2007 and 2012, we identified 103 adults who underwent RFA for SVT in the National Unit of Cardiovascular Surgery (UNICAR) in Guatemala. A decision tree was developed with all clinical outcome parameter estimates obtained from the Adult Electrophysiology Clinic. Costs were obtained from UNICAR's administration. A cost-effectiveness analysis was conducted which evaluated costs and quality adjusted life years (QALYs) to compare interventions in terms of their incremental cost-effectiveness ratios (ICERs).
RESULTS: The first RFA had 83% success and cumulative 94% success was achieved with a second one. The cost of the RFA procedure itself was $5,411. RFA gains 1.46 QALYs and saves $ 7,993 compared to of MT for patients with SVT. This demonstrates that in Guatemala, RFA dominates MT in the management of SVT. Using assumptions based largely on the outcomes in UNICAR, we found that the RFA is highly cost-effective. This is a consistent finding, even after varying assumptions about efficacy, complication rates and quality of life.
CONCLUSIONS: RFA dominates MT by improving quality of life and reducing expenditures when used to treat severely symptomatic patients with SVT in Guatemala. The robustness of these finding to variations in parameter assumptions, suggests these findings may hold in other similar settings.

Entities:  

Keywords:  Cost-effectiveness; cost-utility; radiofrequency ablation; supraventricular tachycardia

Year:  2015        PMID: 26543802      PMCID: PMC4629636          DOI: 10.1016/j.vhri.2015.06.002

Source DB:  PubMed          Journal:  Value Health Reg Issues        ISSN: 2212-1099


  15 in total

1.  Comparison of the cost of radiofrequency catheter modification of the atrioventricular node and medical therapy for drug-refractory atrioventricular node reentrant tachycardia.

Authors:  S J Kalbfleisch; H Calkins; J J Langberg; R el-Atassi; A Leon; M Borganelli; F Morady
Journal:  J Am Coll Cardiol       Date:  1992-06       Impact factor: 24.094

2.  Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium.

Authors:  Roxana Mehran; Sunil V Rao; Deepak L Bhatt; C Michael Gibson; Adriano Caixeta; John Eikelboom; Sanjay Kaul; Stephen D Wiviott; Venu Menon; Eugenia Nikolsky; Victor Serebruany; Marco Valgimigli; Pascal Vranckx; David Taggart; Joseph F Sabik; Donald E Cutlip; Mitchell W Krucoff; E Magnus Ohman; Philippe Gabriel Steg; Harvey White
Journal:  Circulation       Date:  2011-06-14       Impact factor: 29.690

Review 3.  Clinical practice. Evaluation and initial treatment of supraventricular tachycardia.

Authors:  Mark S Link
Journal:  N Engl J Med       Date:  2012-10-11       Impact factor: 91.245

4.  Cost-effectiveness of radiofrequency ablation for supraventricular tachycardia.

Authors:  C H Cheng; G D Sanders; M A Hlatky; P Heidenreich; K M McDonald; B K Lee; M S Larson; D K Owens
Journal:  Ann Intern Med       Date:  2000-12-05       Impact factor: 25.391

5.  Radiofrequency catheter ablation of supraventricular tachycardia in children and adolescents : feasibility and cost-effectiveness in a low-income country.

Authors:  Vladimiro L Vida; Gonzalo S Calvimontes; Maximo O Macs; Patricia Aparicio; Joaquin Barnoya; Aldo R Castañeda
Journal:  Pediatr Cardiol       Date:  2006-07-06       Impact factor: 1.655

6.  Quality of life before and after radiofrequency catheter ablation in patients with drug refractory atrioventricular nodal reentrant tachycardia.

Authors:  M S Larson; K McDonald; C Young; R Sung; M A Hlatky
Journal:  Am J Cardiol       Date:  1999-08-15       Impact factor: 2.778

7.  Paroxysmal supraventricular tachycardia in the general population.

Authors:  L A Orejarena; H Vidaillet; F DeStefano; D L Nordstrom; R A Vierkant; P N Smith; J J Hayes
Journal:  J Am Coll Cardiol       Date:  1998-01       Impact factor: 24.094

8.  Cost-effectiveness of radiofrequency ablation compared with other strategies in Wolff-Parkinson-White syndrome.

Authors:  W Hogenhuis; S K Stevens; P Wang; J B Wong; A S Manolis; N A Estes; S G Pauker
Journal:  Circulation       Date:  1993-11       Impact factor: 29.690

9.  Long-term safety and efficacy of flecainide in the treatment of supraventricular tachyarrhythmias: the United States experience. The Flecainide Supraventricular Tachyarrhythmia Investigators.

Authors:  J L Anderson
Journal:  Am J Cardiol       Date:  1992-08-20       Impact factor: 2.778

10.  Cost-effectiveness of radiofrequency catheter ablation compared with antiarrhythmic drug therapy for paroxysmal atrial fibrillation.

Authors:  Matthew R Reynolds; Peter Zimetbaum; Mark E Josephson; Ethan Ellis; Tatyana Danilov; David J Cohen
Journal:  Circ Arrhythm Electrophysiol       Date:  2009-04-17
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