Literature DB >> 26542217

Late age increase in soluble amyloid-beta levels in the APP23 mouse model despite steady-state levels of amyloid-beta-producing proteins.

Leen Janssen1, Cleo Keppens1, Peter P De Deyn2, Debby Van Dam3.   

Abstract

Entities:  

Keywords:  Aging; Alzheimer's disease; Amyloid-beta; Beta-secretase; Clearance; Gamma-secretase

Mesh：

Substances：

Year:  2015        PMID： 26542217     DOI： 10.1016/j.bbadis.2015.10.027

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


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  5 in total

1.  Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice.

Authors:  Pascale Eede; Juliane Obst; Stefan Prokop; Frank L Heppner; Eileen Benke; Genevieve Yvon-Durocher; Bernhard C Richard; Niclas Gimber; Jan Schmoranzer; Annett Böddrich; Erich E Wanker
Journal:  EMBO Rep       Date:  2020-01-30       Impact factor: 8.807

2.  Prodromal Alzheimer's Disease: Constitutive Upregulation of Neuroglobin Prevents the Initiation of Alzheimer's Pathology.

Authors:  Silvia de Vidania; Irene Palomares-Perez; Ana Frank-García; Takashi Saito; Takaomi C Saido; Jonathan Draffin; María Szaruga; Lucía Chávez-Gutierrez; Miguel Calero; Miguel Medina; Francesc X Guix; Carlos G Dotti
Journal:  Front Neurosci       Date:  2020-12-03       Impact factor: 4.677

3.  The Transglutaminase-2 Interactome in the APP23 Mouse Model of Alzheimer's Disease.

Authors:  Micha M M Wilhelmus; Elisa Tonoli; Clare Coveney; David J Boocock; Cornelis A M Jongenelen; John J P Brevé; Elisabetta A M Verderio; Benjamin Drukarch
Journal:  Cells       Date:  2022-01-24       Impact factor: 6.600

4.  Absence of tissue transglutaminase reduces amyloid-beta pathology in APP23 mice.

Authors:  Micha M M Wilhelmus; Osoul Chouchane; Maarten Loos; Cornelis A M Jongenelen; John J P Brevé; Allert Jonker; John G J M Bol; August B Smit; Benjamin Drukarch
Journal:  Neuropathol Appl Neurobiol       Date:  2022-02-23       Impact factor: 6.250

5.  A novel rhamnoside derivative PL402 up-regulates matrix metalloproteinase 3/9 to promote Aβ degradation and alleviates Alzheimer's-like pathology.

Authors:  Tingting Hu; Yue Zhou; Jing Lu; Peng Xia; Yue Chen; Xin Cao; Gang Pei
Journal:  Aging (Albany NY)       Date:  2020-01-05       Impact factor: 5.682
  5 in total

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