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Literature DB >> 26540093

Penicyclones A-E, Antibacterial Polyketides from the Deep-Sea-Derived Fungus Penicillium sp. F23-2.

Wenqiang Guo¹, Zhenzhen Zhang¹, Tianjiao Zhu¹, Qianqun Gu¹, Dehai Li¹.

Abstract

Five new ambuic acid analogues, penicyclones A-E (1-5), were isolated from the extract of the deep-sea-derived fungus Penicillium sp. F23-2. The structures including the absolute configurations were established by interpretation of NMR and MS data, as well as the application of ECD, X-ray crystallography, and a chemical conversion, as well as the TDDFT-ECD calculations. Penicyclones A-E (1-5) exhibited antimicrobial activity against the Gram-positive bacterium Staphylococcus aureus with MIC values ranging from 0.3 to 1.0 μg/mL.

Entities: Chemical Species

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Year: 2015 PMID： 26540093 DOI： 10.1021/acs.jnatprod.5b00655

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

13 in total

Review 1. Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin.

Authors: Rosario Nicoletti; Antonio Trincone
Journal: Mar Drugs Date: 2016-02-18 Impact factor: 5.118

Review 2. Natural Products Research in China From 2015 to 2016.

Authors: Haishan Liu; Guoliang Zhu; Yaqin Fan; Yuqi Du; Mengmeng Lan; Yibo Xu; Weiming Zhu
Journal: Front Chem Date: 2018-03-20 Impact factor: 5.221

3. Rapid Metabolome and Bioactivity Profiling of Fungi Associated with the Leaf and Rhizosphere of the Baltic Seagrass Zostera marina.

Authors: Lars-Erik Petersen; Michael Marner; Antje Labes; Deniz Tasdemir
Journal: Mar Drugs Date: 2019-07-19 Impact factor: 5.118

Review 4. Marine Pharmacology in 2014-2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors: Alejandro M S Mayer; Aimee J Guerrero; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Fumiaki Nakamura; Nobuhiro Fusetani
Journal: Mar Drugs Date: 2019-12-19 Impact factor: 5.118

Penicyclones A-E, Antibacterial Polyketides from the Deep-Sea-Derived Fungus Penicillium sp. F23-2.

Review 1. Bioactive Compounds Produced by Strains of Penicillium and Talaromyces of Marine Origin.

Review 2. Natural Products Research in China From 2015 to 2016.

3. Rapid Metabolome and Bioactivity Profiling of Fungi Associated with the Leaf and Rhizosphere of the Baltic Seagrass Zostera marina.

Review 4. Marine Pharmacology in 2014-2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Review 5. Novel Natural Products from Extremophilic Fungi.

6. Sorbicillasins A⁻B and Scirpyrone K from a Deep-Sea-Derived Fungus, Phialocephala sp. FL30r.

Review 7. Antibiotics from Deep-Sea Microorganisms: Current Discoveries and Perspectives.

8. Peniginsengins B⁻E, New Farnesylcyclohexenones from the Deep Sea-Derived Fungus Penicillium sp. YPGA11.

Review 9. Extending the "One Strain Many Compounds" (OSMAC) Principle to Marine Microorganisms.

10. Fungal Diversity in Intertidal Mudflats and Abandoned Solar Salterns as a Source for Biological Resources.