Bellal Joseph1, Ansab Haider, Peter Rhee. 1. Division of Trauma and Acute Care Surgery, Department of Surgery, University of Arizona Medical Center, Tucson, Arizona, USA.
Abstract
PURPOSE OF REVIEW: Traumatic brain injury (TBI) remains the leading cause of morbidity and mortality in the United States. Over the last decade, several advancements have been made in the field of TBI all aimed at improving outcomes. RECENT FINDINGS: Advancements in the management of TBI have been made possible through improved understanding of basic pathophysiology associated with this condition. The aim of this review is to briefly highlight the underlying pathophysiology of TBI and the most recent advancements and novel strategies being used in its treatment. We also briefly discuss coagulopathy of TBI, clinical management of TBI and how it has evolved recently. SUMMARY: The mortality associated with TBI continues to remain high and several novel strategies have emerged as potential candidates for the treatment of secondary brain injury. The clinical management of TBI and associated coagulopathy has evolved allowing for a more tailored approach toward its management.
PURPOSE OF REVIEW: Traumatic brain injury (TBI) remains the leading cause of morbidity and mortality in the United States. Over the last decade, several advancements have been made in the field of TBI all aimed at improving outcomes. RECENT FINDINGS: Advancements in the management of TBI have been made possible through improved understanding of basic pathophysiology associated with this condition. The aim of this review is to briefly highlight the underlying pathophysiology of TBI and the most recent advancements and novel strategies being used in its treatment. We also briefly discuss coagulopathy of TBI, clinical management of TBI and how it has evolved recently. SUMMARY: The mortality associated with TBI continues to remain high and several novel strategies have emerged as potential candidates for the treatment of secondary brain injury. The clinical management of TBI and associated coagulopathy has evolved allowing for a more tailored approach toward its management.
Authors: Yu Liu; Samuel S McAfee; Natalie M Guley; Nobel Del Mar; Wei Bu; Scott A Heldt; Marcia G Honig; Bob M Moore; Anton Reiner; Detlef H Heck Journal: eNeuro Date: 2017-08-18