| Literature DB >> 2653894 |
L A Kollée1, I Speyer, M A van Kuijck, R Koopman, J M Dony, J H Bakker, R G Wintermans.
Abstract
In a prospective study in 227 parturients, carriership of group B streptococci was established to be 25%. In carriers, transmission of streptococci to the newborn occurred in 50%. 10 ml of a chlorhexidine gel containing hydroxypropylmethylcellulose was introduced into the vagina during labor in 17 parturients, who were known to be carriers of group B streptococci from the first trimester of pregnancy. In none of the newborns from these mothers colonization by group B streptococci did occur. Vaginal application of chlorhexidine may prevent transmission of group B streptococci, and serve as an alternative to intrapartum prophylaxis using antibiotics. A large multicenter randomized controlled study should be performed to confirm this hypothesis.Entities:
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Year: 1989 PMID： 2653894 DOI： 10.1016/0028-2243(89)90025-7
Source DB: PubMed Journal: Eur J Obstet Gynecol Reprod Biol ISSN： 0301-2115 Impact factor: 2.435