Literature DB >> 26538671

Successful treatment of a cat with primary hypoadrenocorticism and severe hyponatremia with desoxycorticosterone pivalate (DOCP).

Andrew D Woolcock1, Cynthia Ward1.   

Abstract

A 6-year-old, castrated male Siamese cat was diagnosed with primary hypoadrenocorticism, confirmed by an adrenocorticotopic hormone (ACTH) stimulation test documenting both hypocortisolism and hypoaldosteronism. The cat was successfully treated using a combination of prednisolone and desoxycorticosterone pivalate (DOCP). This case demonstrates that DOCP can be used successfully as mineralocorticoid supplementation in cats with hypoadrenocorticism and may have a longer therapeutic duration than that in dogs.

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Year:  2015        PMID: 26538671      PMCID: PMC4608469     

Source DB:  PubMed          Journal:  Can Vet J        ISSN: 0008-5286            Impact factor:   1.008


  17 in total

1.  Hypoadrenocorticism in a cat.

Authors:  J Stonehewer; S Tasker
Journal:  J Small Anim Pract       Date:  2001-04       Impact factor: 1.522

2.  Hypercalcemia due to latrogenic secondary hypoadrenocorticism and diabetes mellitus in a cat.

Authors:  Stephanie A Smith; Lisa C Freeman; Mary Bagladi-Swanson
Journal:  J Am Anim Hosp Assoc       Date:  2002 Jan-Feb       Impact factor: 1.023

3.  A case of feline primary hypoadrenocorticism.

Authors:  S Tasker; A D MacKay; A H Sparkes
Journal:  J Feline Med Surg       Date:  1999-12       Impact factor: 2.015

4.  Primary hypoadrenocorticism in ten cats.

Authors:  M E Peterson; D S Greco; D N Orth
Journal:  J Vet Intern Med       Date:  1989 Apr-Jun       Impact factor: 3.333

Review 5.  Diagnosis and management of primary spontaneous hypoadrenocorticism (Addison's disease) in dogs.

Authors:  P P Kintzer; M E Peterson
Journal:  Semin Vet Med Surg (Small Anim)       Date:  1994-08

6.  Validation of nonradioactive chemiluminescent immunoassay methods for the analysis of thyroxine and cortisol in blood samples obtained from dogs, cats, and horses.

Authors:  A K Singh; Y Jiang; T White; D Spassova
Journal:  J Vet Diagn Invest       Date:  1997-07       Impact factor: 1.279

7.  Treatment and long-term follow-up of 205 dogs with hypoadrenocorticism.

Authors:  P P Kintzer; M E Peterson
Journal:  J Vet Intern Med       Date:  1997 Mar-Apr       Impact factor: 3.333

Review 8.  Primary and secondary canine hypoadrenocorticism.

Authors:  P P Kintzer; M E Peterson
Journal:  Vet Clin North Am Small Anim Pract       Date:  1997-03       Impact factor: 2.093

9.  Toxicity of desoxycorticosterone pivalate given at high dosages to clinically normal beagles for six months.

Authors:  E Chow; W R Campbell; J C Turnier; R C Lynn; K L Pavkov
Journal:  Am J Vet Res       Date:  1993-11       Impact factor: 1.156

10.  Efficacy of microcrystalline desoxycorticosterone pivalate for treatment of hypoadrenocorticism in dogs. DOCP Clinical Study Group.

Authors:  R C Lynn; E C Feldman; R W Nelson
Journal:  J Am Vet Med Assoc       Date:  1993-02-01       Impact factor: 1.936

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