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Literature DB >> 26538670

Primary portal vein hypoplasia and SLC2A9 mutation associated with urate urolithiasis in a Spanish water dog.

Laura Cosgrove¹, Gawain Hammond¹, Gerard Mclauchlan¹.

Abstract

This report describes a Spanish water dog with an ammonium urate urethrolith which was diagnosed with primary portal vein hypoplasia and was found to be homozygous for the mutated SLC2A9 gene. This is the first Spanish water dog described with the SLC2A9 mutation and the first case of concurrent portal vascular abnormalities and SLC2A9 mutation.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2015 PMID： 26538670 PMCID： PMC4608468

Source DB: PubMed Journal: Can Vet J ISSN： 0008-5286 Impact factor: 1.008

20 in total

1. Pharmacokinetics of allopurinol in Dalmatian dogs.

Authors: G V Ling; L C Case; H Nelson; D R Harrold; D L Johnson; P R Vulliet
Journal: J Vet Pharmacol Ther Date: 1997-04 Impact factor: 1.786

2. High prevalence of urate urolithiosis in the Russian black terrier.

Authors: B Bende; T Németh
Journal: Vet Rec Date: 2004-08-21 Impact factor: 2.695

Review 3. Acute phase proteins in dogs and cats: current knowledge and future perspectives.

Authors: Jose Joaquýn Ceron; Peter David Eckersall; Silvia Martýnez-Subiela
Journal: Vet Clin Pathol Date: 2005-06 Impact factor: 1.180

Review 4. The Dalmatian defect: a hepatic endocrinopathy of urate transport.

Authors: Peter A Simkin
Journal: Arthritis Rheum Date: 2005-08

5. Clinicopathologic features of dogs with hepatic microvascular dysplasia with and without portosystemic shunts: 42 cases (1991-1996).

Authors: L Allen; D Stobie; G N Mauldin; K E Baer
Journal: J Am Vet Med Assoc Date: 1999-01-15 Impact factor: 1.936

Primary portal vein hypoplasia and SLC2A9 mutation associated with urate urolithiasis in a Spanish water dog.

1. Pharmacokinetics of allopurinol in Dalmatian dogs.

2. High prevalence of urate urolithiosis in the Russian black terrier.

Review 3. Acute phase proteins in dogs and cats: current knowledge and future perspectives.

Review 4. The Dalmatian defect: a hepatic endocrinopathy of urate transport.

5. Clinicopathologic features of dogs with hepatic microvascular dysplasia with and without portosystemic shunts: 42 cases (1991-1996).

6. Characterization of hepatoportal microvascular dysplasia in a kindred of cairn terriers.

7. Comparison of postprandial and ceruletide serum bile acid stimulation in dogs.

8. Congenital portosystemic shunts in dogs: 46 cases (1979-1986).

9. Urinary calculi associated with portosystemic shunts in six dogs.

10. Mutations in the SLC2A9 gene cause hyperuricosuria and hyperuricemia in the dog.

1. Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011-2012).