Literature DB >> 26538363

Synthesis, Characterization and Fluorescence Properties of Zn(II) and Cu(II) Complexes: DNA Binding Study of Zn(II) Complex.

Parirokh Lavaee1, Hossein Eshtiagh-Hosseini2, Mohammad Reza Housaindokht1, Joel T Mague3, Abbas Ali Esmaeili1, Khalil Abnous4.   

Abstract

Zinc(II) and copper(II) complexes containing Schiff base, 2- methoxy-6((E)-(phenylimino) methyl) phenol ligand (HL) were synthesized and characterized by elemental analysis, IR, NMR, and single crystal X-ray diffraction technique. The fluorescence properties and quantum yield of zinc complex were studied. Our data showed that Zn complex could bind to DNA grooves with Kb = 10(4) M(-1). Moreover, Zn complex could successfully be used in staining of DNA following agarose gel electrophoresis. MTT assay showed that Zn complex was not cytotoxic in MCF-7 cell line. Here, we introduce a newly synthesized fluorescence probe that can be used for single and double stranded DNA detection in both solution and agarose gels.

Entities:  

Keywords:  Copper; DNA; Fluorescence; Interaction; Schiff base; Zinc

Mesh：

Substances：

Year:  2015        PMID： 26538363     DOI： 10.1007/s10895-015-1719-6

Source DB:  PubMed          Journal:  J Fluoresc        ISSN： 1053-0509            Impact factor:   2.217


  25 in total

1.  Characterization of SYBR Gold nucleic acid gel stain: a dye optimized for use with 300-nm ultraviolet transilluminators.

Authors:  R S Tuma; M P Beaudet; X Jin; L J Jones; C Y Cheung; S Yue; V L Singer
Journal:  Anal Biochem       Date:  1999-03-15       Impact factor: 3.365

2.  Red-fluorescent argininamide-type NPY Y1 receptor antagonists as pharmacological tools.

Authors:  Max Keller; Daniela Erdmann; Nathalie Pop; Nikola Pluym; Shangjun Teng; Günther Bernhardt; Armin Buschauer
Journal:  Bioorg Med Chem       Date:  2011-04-12       Impact factor: 3.641

3.  Structural variation in copper(I) complexes with pyridylmethylamide ligands: structural analysis with a new four-coordinate geometry index, tau4.

Authors:  Lei Yang; Douglas R Powell; Robert P Houser
Journal:  Dalton Trans       Date:  2007-01-29       Impact factor: 4.390

4.  New luminescent terbium complex for the determination of DNA.

Authors:  Alla Yegorova; Alexander Karasyov; Axel Duerkop; Igor Ukrainets; Valery Antonovich
Journal:  Spectrochim Acta A Mol Biomol Spectrosc       Date:  2005-01-01       Impact factor: 4.098

5.  Carbon nanotube-enhanced DNA biosensor for DNA hybridization detection using manganese(II)-Schiff base complex as hybridization indicator.

Authors:  Shuyan Niu; Min Zhao; Rui Ren; Shusheng Zhang
Journal:  J Inorg Biochem       Date:  2008-09-18       Impact factor: 4.155

6.  [Ru(phen)2(dppz)]2+ as an efficient optical probe for staining nuclear components.

Authors:  Venugopal Rajendiran; Mallayan Palaniandavar; Vaiyapuri Subbarayan Periasamy; Mohammad Abdulkader Akbarsha
Journal:  J Inorg Biochem       Date:  2009-10-23       Impact factor: 4.155

7.  Sensitization to doxorubicin resistance in breast cancer cell lines by tamoxifen and megestrol acetate.

Authors:  L Panasci; B J Jean-Claude; D Vasilescu; A Mustafa; S Damian; Z Damian; E Georges; Z Liu; G Batist; B Leyland-Jones
Journal:  Biochem Pharmacol       Date:  1996-10-11       Impact factor: 5.858

8.  Synthesis, DNA interaction and anticancer activity of copper(II) complexes with 4'-phenyl-2,2':6',2″-terpyridine derivatives.

Authors:  Jie-Wen Liang; Yi Wang; Ke-Jie Du; Guan-Ying Li; Rui-Lin Guan; Liang-Nian Ji; Hui Chao
Journal:  J Inorg Biochem       Date:  2014-08-19       Impact factor: 4.155

Review 9.  Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors.

Authors:  Nathan W Luedtke; Yitzhak Tor
Journal:  Biopolymers       Date:  2003-09       Impact factor: 2.505

10.  Molecular aspects on the interaction of isatin-3-isonicotinylhydrazone to deoxyribonucleic acid: model for intercalative drug-DNA binding.

Authors:  Soheila Kashanian; Mohammad Mehdi Khodaei; Parvaneh Pakravan; Hadi Adibi
Journal:  Mol Biol Rep       Date:  2011-07-21       Impact factor: 2.742
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  1 in total

1.  Design of New Schiff-Base Copper(II) Complexes: Synthesis, Crystal Structures, DFT Study, and Binding Potency toward Cytochrome P450 3A4.

Authors:  Tunde L Yusuf; Segun D Oladipo; Sizwe Zamisa; Hezekiel M Kumalo; Isiaka A Lawal; Monsurat M Lawal; Nonhlangabezo Mabuba
Journal:  ACS Omega       Date:  2021-05-19
  1 in total

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