| Literature DB >> 26538362 |
Xiaohe Tian1,2, Hui Wang3, Lijuan Guan4, Qiong Zhang3, Hongping Zhou3, Chunxia Li5, Bei Huang5, Jieying Wu3, Yupeng Tian6.
Abstract
In this letter, aggregation from two-photon absorption (2PA) molecules in living cells were firstly observed and the related aggregation induced emission (AIE) properties were investigated as a cell tracer for L ((Z)-3-(4-(Bis(4-ethoxyphenyl) amino)phenyl)-2-(4-amino-phenyl)- acrylonitrile cyano-substituted ) based on triphenylamine with D-π-A model. L was further used as a two-photon absorption (2PA, λex = 900, λem = 550 nm δ = 156 GM) live-cell marker for real-time, long-term cell growth and proliferation monitoring, with rapidly adhering whole intracellular membrane-rich system. Remarkably, different from existing organic AIE chromophores and other commercially available probes, L exhibited intense intracellular-AIE property with stable nuclear envelope (NE) staining under two-photon excited microscopy (TPEM) through detailed in cellulo studies.Entities:
Keywords: Aggregation induced emission; Live-cell image; Nuclear envelope; Real-time; Two-photon absorption
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Year: 2015 PMID： 26538362 DOI： 10.1007/s10895-015-1703-1
Source DB: PubMed Journal: J Fluoresc ISSN： 1053-0509 Impact factor: 2.217