Literature DB >> 2653763

Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase.

W Dekant1, S Vamvakas, M W Anders.   

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Year:  1989        PMID: 2653763     DOI: 10.3109/03602538908994144

Source DB:  PubMed          Journal:  Drug Metab Rev        ISSN: 0360-2532            Impact factor:   4.518


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  9 in total

1.  Studies of the mechanism of nephrotoxicity of compound A in rats.

Authors:  J L Martin; L Kandel; M J Laster; R L Kerschmann; E I Eger
Journal:  J Anesth       Date:  1997-03       Impact factor: 2.078

2.  Renal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation.

Authors:  Schantel A Hayes; Arun R Pandiri; Thai-vu T Ton; Hue-Hua L Hong; Natasha P Clayton; Keith R Shockley; Shyamal D Peddada; Kevin Gerrish; Michael Wyde; Robert C Sills; Mark J Hoenerhoff
Journal:  Toxicol Pathol       Date:  2015-12-17       Impact factor: 1.902

3.  The nephrotoxin dichlorovinylcysteine induces expression of the protooncogenes c-fos and c-myc in LLC-PK1 cells--a comparative investigation with growth factors and 12-O-tetradecanoylphorbolacetate.

Authors:  S Vamvakas; U Köster
Journal:  Cell Biol Toxicol       Date:  1993 Jan-Mar       Impact factor: 6.691

4.  Mutagenicity and cytotoxicity of two regioisomeric mercapturic acids and cysteine S-conjugates of trichloroethylene.

Authors:  J N Commandeur; P J Boogaard; G J Mulder; N P Vermeulen
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

5.  Alterations of the renal function in the isolated perfused rat kidney system after in vivo and in vitro application of S-(1,2-dichlorovinyl)-L-cysteine and S-(2,2-dichlorovinyl)-L-cysteine.

Authors:  O Ilinskaja; S Vamvakas
Journal:  Arch Toxicol       Date:  1996       Impact factor: 5.153

6.  Bioactivation of cysteine conjugates of 1-nitropyrene oxides by cysteine conjugate beta-lyase purified from Peptostreptococcus magnus.

Authors:  K Kataoka; T Kinouchi; S Akimoto; Y Ohnishi
Journal:  Appl Environ Microbiol       Date:  1995-11       Impact factor: 4.792

7.  Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene.

Authors:  D Henschler; S Vamvakas; M Lammert; W Dekant; B Kraus; B Thomas; K Ulm
Journal:  Arch Toxicol       Date:  1995       Impact factor: 5.153

8.  Nephrotoxicity of 4-amino-3-S-glutathionylphenol and its modulation by metabolism or transport inhibitors.

Authors:  L M Fowler; J R Foster; E A Lock
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

Review 9.  A mechanism of haloalkene-induced renal carcinogenesis.

Authors:  W Dekant; S Vamvakas; M Koob; A Köchling; W Kanhai; D Müller; D Henschler
Journal:  Environ Health Perspect       Date:  1990-08       Impact factor: 9.031

  9 in total

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