| Literature DB >> 26536379 |
Abstract
TRIB1, a homolog of Drosophila Tribbles, regulates the stability of transcription factors through physical interaction with the ubiquitin E3 ligase COP1. In this issue of Structure, Murphy et al. (2015) report the first X-ray analysis of the TRIB1 pseudokinase domain and its C-terminal COP1-binding extension.Entities:
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Year: 2015 PMID： 26536379 DOI： 10.1016/j.str.2015.10.003
Source DB: PubMed Journal: Structure ISSN： 0969-2126 Impact factor: 5.006