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Literature DB >> 2653244

Selective depletion and activation of CD8+ lymphocytes from peripheral blood of patients with polymyalgia rheumatica and giant cell arteritis.

B Dasgupta¹, O Duke, A M Timms, C Pitzalis, G S Panayi.

Abstract

A prospective study of 33 patients with polymyalgia rheumatica/giant cell arteritis (PMR/GCA) was undertaken, firstly, to monitor sequentially peripheral blood CD8+ lymphocyte levels and, secondly, to assess the expression of activation markers on T lymphocyte subsets. The results indicated that there was a significant decrease in absolute numbers and relative percentages of CD8+ T lymphocytes, which returned to normal ranges after approximately 24 months' treatment, and that there was an increased percentage of CD8+ lymphocytes in PMR/GCA which express HLA class II antigens.

Entities: Disease Gene Species

Mesh：

Year: 1989 PMID： 2653244 PMCID： PMC1003746 DOI： 10.1136/ard.48.4.307

Source DB: PubMed Journal: Ann Rheum Dis ISSN： 0003-4967 Impact factor: 19.103

12 in total

1. Does Kawasaki disease have a retroviral aetiology?

Authors: S T Shulman; A H Rowley
Journal: Lancet Date: 1986-09-06 Impact factor: 79.321

2. Antibodies to intermediate filaments in polymyalgia rheumatica and giant cell arteritis: a sequential study.

Authors: B Dasgupta; O Duke; V Kyle; D G Macfarlane; B L Hazleman; G S Panayi
Journal: Ann Rheum Dis Date: 1987-10 Impact factor: 19.103

3. Decreased level of suppressor/cytotoxic T cells (OKT8+) in polymyalgia rheumatica and temporal arteritis: relation to disease activity.

Authors: H Elling; P Elling
Journal: J Rheumatol Date: 1985-04 Impact factor: 4.666

4. Immunohistologic and cytochemical studies of temporal arteritis.

Authors: P M Banks; M D Cohen; W W Ginsburg; G G Hunder
Journal: Arthritis Rheum Date: 1983-10

5. Histocompatibility antigens in polymyalgia rheumatica and giant cell arteritis.

Authors: R D Armstrong; A Behn; A Myles; G S Panayi; K I Welsh
Journal: J Rheumatol Date: 1983-08 Impact factor: 4.666

6. Serum levels of immunoglobulin and complement in giant-cell arteritis.

Authors: B E Malmvall; B A Bengtsson; B Kaijser; L A Nilsson; K Alestig
Journal: JAMA Date: 1976-10-18 Impact factor: 56.272

7. Decrease of the OKT8 positive T cell subset in polymyalgia rheumatica. Lack of correlation with disease activity.

Authors: C Benlahrache; P Segond; L Auquier; J P Bouvet
Journal: Arthritis Rheum Date: 1983-12

8. An AIDS-related cytotoxic autoantibody reacts with a specific antigen on stimulated CD4+ T cells.

Authors: R B Stricker; T M McHugh; D J Moody; W J Morrow; D P Stites; M A Shuman; J A Levy
Journal: Nature Date: 1987 Jun 25-Jul 1 Impact factor: 49.962

9. Polymyalgia rheumatica and giant cell arteritis: circulating immune complexes.

Authors: L R Espinoza; P Bridgeford; M Lowenstein; T S Bocanegra; F B Vasey; B F Germain
Journal: J Rheumatol Date: 1982 Jul-Aug Impact factor: 4.666

10. Polymerase activity in lymphocyte culture supernatants from patients with Kawasaki disease.

Authors: J C Burns; R S Geha; E E Schneeberger; J W Newburger; F S Rosen; L S Glezen; A S Huang; J Natale; D Y Leung
Journal: Nature Date: 1986 Oct 30-Nov 5 Impact factor: 49.962

22 in total

1. Giant cell arteritis.

Authors: L G Clearkin
Journal: BMJ Date: 1992-08-29

Review 2. Stopping steroids in polymyalgia rheumatica and giant cell arteritis.

Authors: V Kyle; B L Hazelman
Journal: BMJ Date: 1990-02-10

3. Inflammation of the uveal tract as a presenting feature of temporal arteritis.

Authors: B Dasgupta; C Pitzalis; G S Panayi
Journal: Ann Rheum Dis Date: 1989-11 Impact factor: 19.103

4. Peripheral blood lymphocyte subsets in polymyalgia rheumatica.

Authors: A Uddhammar; G Roos; B Näsman; S R Dahlqvist
Journal: Clin Rheumatol Date: 1995-01 Impact factor: 2.980

5. Circulating T cell subtypes in polymyalgia rheumatica and giant cell arteritis: variation in the percentage of CD8+ cells with prednisolone treatment.

Authors: G S Panayi
Journal: Ann Rheum Dis Date: 1994-04 Impact factor: 19.103

6. Circulating T cell subtypes in polymyalgia rheumatica and giant cell arteritis: variation in the percentage of CD8+ cells with prednisolone treatment.

Authors: G D Pountain; M T Keogan; D L Brown; B L Hazleman
Journal: Ann Rheum Dis Date: 1993-10 Impact factor: 19.103

7. T lymphocytes in giant cell arteritic lesions are polyclonal cells expressing alpha beta type antigen receptors and VLA-1 integrin receptors.

Authors: C Schaufelberger; S Stemme; R Andersson; G K Hansson
Journal: Clin Exp Immunol Date: 1993-03 Impact factor: 4.330