Literature DB >> 26531739

Immune recovery uveitis in a patient with previously undiagnosed cytomegalovirus retinitis.

Carlos Mario Rangel1, Angélica M Prada2, Clara Varon3, Jesus Merayo-Lloves4.   

Abstract

A 40-year-old man presented to the emergency service of the Department of Ophthalmology, Fundación Oftalmológica de Santander, Floridablanca, Colombia, with blurred vision in his right eye. Anamnesis revealed that he also had newly diagnosed stage C HIV. He had recently started highly active antiretroviral therapy (HAART). Examination disclosed intraocular inflammation, along with plain white peripheral non-exudative lesions with sparse haemorrhaging. The differential diagnosis included cytomegalovirus (CMV) retinitis and immune recovery uveitis (IRU). On follow-up, the patient's left eye presented with decreased visual acuity and increased vitreous haze. A vitrectomy with vitreous tap was performed for microbiological studies. PCR for CMV in the vitreous sample was negative. The patient was discharged with the final diagnosis of IRU. In HIV patients with uveitis, the knowledge of characteristic signs and symptoms of particular entities such as opportunistic infections and IRU will enable the clinician to give the appropriate treatment. 2015 BMJ Publishing Group Ltd.

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Mesh:

Year:  2015        PMID: 26531739      PMCID: PMC4654151          DOI: 10.1136/bcr-2015-212095

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  21 in total

1.  Cytomegalovirus retinitis and the acquired immunodeficiency syndrome--bench to bedside: LXVII Edward Jackson Memorial Lecture.

Authors:  Douglas A Jabs
Journal:  Am J Ophthalmol       Date:  2010-12-18       Impact factor: 5.258

Review 2.  Endogenous bacterial and fungal endophthalmitis.

Authors:  Stephen R Smith; Arnold J Kroll; Peter L Lou; Edward A Ryan
Journal:  Int Ophthalmol Clin       Date:  2007

3.  Immune-recovery posterior uveitis associated with inactive isolated toxoplasmic retinochoroiditis in a patient with human immunodeficiency virus.

Authors:  Susana Ruiz Bilbao; Sandra Gómez Sánchez; Cristina Tural Llacher; Ramón Anglada Escalona; Laura Broc Iturralde; Alberto Aranda Yus; Guillem Sirera Jimenez; Bonaventura Clotet
Journal:  Retin Cases Brief Rep       Date:  2012

4.  Ocular tuberculosis in acquired immunodeficiency syndrome.

Authors:  Rajesh B Babu; Sridharan Sudharshan; Nagalingeswaran Kumarasamy; Lily Therese; Jyotirmay Biswas
Journal:  Am J Ophthalmol       Date:  2006-09       Impact factor: 5.258

Review 5.  CMV retinitis in the era of HAART.

Authors:  N Cassoux; B Bodaghi; C Katlama; P LeHoang
Journal:  Ocul Immunol Inflamm       Date:  1999-12       Impact factor: 3.070

6.  Rapidly progressive outer retinal necrosis in the acquired immunodeficiency syndrome.

Authors:  D J Forster; P U Dugel; G T Frangieh; P E Liggett; N A Rao
Journal:  Am J Ophthalmol       Date:  1990-10-15       Impact factor: 5.258

7.  Risk of immune recovery uveitis in patients with AIDS and cytomegalovirus retinitis.

Authors:  John H Kempen; Yuan-I Min; William R Freeman; Gary N Holland; Dorothy N Friedberg; Douglas T Dieterich; Douglas A Jabs
Journal:  Ophthalmology       Date:  2006-04       Impact factor: 12.079

Review 8.  Posterior segment manifestations of HIV/AIDS.

Authors:  Tamara R Vrabec
Journal:  Surv Ophthalmol       Date:  2004 Mar-Apr       Impact factor: 6.048

Review 9.  Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop.

Authors:  Douglas A Jabs; Robert B Nussenblatt; James T Rosenbaum
Journal:  Am J Ophthalmol       Date:  2005-09       Impact factor: 5.258

10.  Immune recovery uveitis masked as an endogenous endophthalmitis in a patient with active CMV retinitis.

Authors:  Ligia Figueiredo; Renata Rothwell; Miguel Bilhoto; Rosário Varandas; Sofia Fonseca
Journal:  Case Rep Ophthalmol Med       Date:  2013-04-09
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  2 in total

1.  Intravitreal aflibercept for treatment of macular oedema associated with immune recovery uveitis.

Authors:  Aniki Rothova; Josianne C Ten Berge; Johannes R Vingerling
Journal:  Acta Ophthalmol       Date:  2020-04-30       Impact factor: 3.761

2.  Do we need separate screening strategies for cytomegalovirus retinitis in different underlying immunosuppressed states? A retrospective study from Western India.

Authors:  Bindiya Doshi; Niha Z Khatib; Sumita Phatak; Rohit Modi; Sarvesh Tiwari; Anand Subramanyam
Journal:  Indian J Ophthalmol       Date:  2021-03       Impact factor: 1.848

  2 in total

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