Literature DB >> 26531136

Surface polysaccharides from Acinetobacter baumannii: Structures and syntheses.

Denis Giguère1.   

Abstract

The emergence of multidrug-resistance Acinetobacter baumannii requires novel approaches for prevention, treatment and diagnosis. The structures of surface polysaccharides from A. baumannii are valuable tools to understand pathogenesis, virulence and immunogenicity. The synthesis of bacterial mono- or polysaccharides may result in novel probes to become important therapeutic options in the fight against A. baumannii. This report exemplifies the relevance of glycochemistry for the development of new antibiotics.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Acinetobacter baumannii; Capsular polysaccharides; Lipopolysaccharides; Polysaccharide synthesis; Surface polysaccharides

Mesh：

Substances：

Year:  2015        PMID： 26531136     DOI： 10.1016/j.carres.2015.10.001

Source DB:  PubMed          Journal:  Carbohydr Res        ISSN： 0008-6215            Impact factor:   2.104


  6 in total

1.  Crystal structure of a UDP-GlcNAc epimerase for surface polysaccharide biosynthesis in Acinetobacter baumannii.

Authors:  Bhumika S Shah; Heather E Ashwood; Stephen J Harrop; Daniel N Farrugia; Ian T Paulsen; Bridget C Mabbutt
Journal:  PLoS One       Date:  2018-01-19       Impact factor: 3.240

2.  Abundance and co-occurrence of extracellular capsules increase environmental breadth: Implications for the emergence of pathogens.

Authors:  Olaya Rendueles; Marc Garcia-Garcerà; Bertrand Néron; Marie Touchon; Eduardo P C Rocha
Journal:  PLoS Pathog       Date:  2017-07-24       Impact factor: 6.823

3.  Nutrient conditions are primary drivers of bacterial capsule maintenance in Klebsiella.

Authors:  Amandine Buffet; Eduardo P C Rocha; Olaya Rendueles
Journal:  Proc Biol Sci       Date:  2021-03-03       Impact factor: 5.349

4.  Total Synthesis of an All-1,2-cis-Linked Repeating Unit from the Acinetobacter baumannii D78 Capsular Polysaccharide.

Authors:  Dancan K Njeri; Justin R Ragains
Journal:  Org Lett       Date:  2022-05-06       Impact factor: 6.072

Review 5.  Mechanisms Protecting Acinetobacter baumannii against Multiple Stresses Triggered by the Host Immune Response, Antibiotics and Outside-Host Environment.

Authors:  Soroosh Monem; Beata Furmanek-Blaszk; Adrianna Łupkowska; Dorota Kuczyńska-Wiśnik; Karolina Stojowska-Swędrzyńska; Ewa Laskowska
Journal:  Int J Mol Sci       Date:  2020-07-31       Impact factor: 5.923

6.  Safety and immunogenicity of a new glycoengineered vaccine against Acinetobacter baumannii in mice.

Authors:  Xin Li; Chao Pan; Zhicheng Liu; Peng Sun; Xiaoting Hua; Erling Feng; Yunsong Yu; Jun Wu; Li Zhu; Hengliang Wang
Journal:  Microb Biotechnol       Date:  2021-03-23       Impact factor: 5.813
  6 in total

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