Literature DB >> 26530709

Parametric study of ventricular catheters for hydrocephalus.

Marcelo Galarza1, Angel Giménez2, Olga Pellicer3, José Valero2, José M Amigó2.   

Abstract

BACKGROUND: To drain the excess of cerebrospinal fluid in a hydrocephalus patient, a catheter is inserted into one of the brain ventricles and then connected to a valve. This so-called ventricular catheter is a standard-size, flexible tubing with a number of holes placed symmetrically around several transversal sections or "drainage segments". Three-dimensional computational dynamics shows that most of the fluid volume flows through the drainage segment closest to the valve. This fact raises the likelihood that those holes and then the lumen get clogged by the cells and macromolecules present in the cerebrospinal fluid, provoking malfunction of the whole system. In order to better understand the flow pattern, we have carried out a parametric study via numerical models of ventricular catheters.
METHODS: The parameters chosen are the number of drainage segments, the distances between them, the number and diameter of the holes on each segment, as well as their relative angular position.
RESULTS: These parameters were found to have a direct consequence on the flow distribution and shear stress of the catheter. As a consequence, we formulate general principles for ventricular catheter design.
CONCLUSIONS: These principles can help develop new catheters with homogeneous flow patterns, thus possibly extending their lifetime.

Entities:  

Keywords:  Cerebrospinal fluid (CSF); Computational fluid dynamics (CFD); Flow; Hydrocephalus; New designs; Obstruction; Parameters; Shunt; Ventricular catheter (VC)

Mesh:

Year:  2015        PMID: 26530709     DOI: 10.1007/s00701-015-2618-y

Source DB:  PubMed          Journal:  Acta Neurochir (Wien)        ISSN: 0001-6268            Impact factor:   2.216


  4 in total

1.  Pulsatile flow in ventricular catheters for hydrocephalus.

Authors:  Á Giménez; M Galarza; U Thomale; M U Schuhmann; J Valero; J M Amigó
Journal:  Philos Trans A Math Phys Eng Sci       Date:  2017-06-28       Impact factor: 4.226

2.  Next generation of ventricular catheters for hydrocephalus based on parametric designs.

Authors:  M Galarza; A Giménez; J M Amigó; M Schuhmann; R Gazzeri; U Thomale; J P McAllister
Journal:  Childs Nerv Syst       Date:  2017-08-15       Impact factor: 1.475

3.  Computational Modeling and Simulation to Quantify the Effects of Obstructions on the Performance of Ventricular Catheters Used in Hydrocephalus Treatment.

Authors:  Stephanie TerMaath; Douglas Stefanski; James Killeffer
Journal:  Methods Mol Biol       Date:  2022

4.  Influence of the hole geometry on the flow distribution in ventricular catheters for hydrocephalus.

Authors:  Ángel Giménez; Marcelo Galarza; Olga Pellicer; José Valero; José M Amigó
Journal:  Biomed Eng Online       Date:  2016-07-15       Impact factor: 2.819

  4 in total

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