Literature DB >> 26530335

Patterns of Alcohol Use after Traumatic Brain Injury.

Kathleen F Pagulayan1,2, Nancy R Temkin3,4,5, Joan E Machamer3, Sureyya S Dikmen2,3,4.   

Abstract

Alcohol misuse and traumatic brain injury (TBI) frequently co-occur. The negative consequences of this interaction are well documented, but the patterns of long-term post-injury alcohol consumption are less clear. This study examined patterns of alcohol use among 170 adults with a history of complicated mild to severe TBI. Participants were recruited from a Level 1 Trauma Center at the time of their injury and completed evaluations at 1 month, 6 months, 12 months, and 3-5 years post-injury. Pre-injury alcohol use was also assessed at the time of the 1-month assessment. A modified Quantity-Frequency Index of alcohol consumption was then calculated for each time point. The results revealed high levels of pre-injury alcohol consumption, followed by a reduction in consumption at 1-month post-injury. A significant increase in consumption was noted by 6 months post-injury, followed by more gradual increases in alcohol consumption at 1 year. Post-injury alcohol consumption was comparable to the general public at 6 months, 12 months, and 3-5 years post-injury. These results suggest that the first 6 months post-injury may be the critical window of opportunity for alcohol intervention.

Entities:  

Keywords:  alcohol; traumatic brain injury

Mesh:

Year:  2016        PMID: 26530335      PMCID: PMC4931769          DOI: 10.1089/neu.2015.4071

Source DB:  PubMed          Journal:  J Neurotrauma        ISSN: 0897-7151            Impact factor:   5.269


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Authors:  S Dikmen; J Machamer; N Temkin; A McLean
Journal:  J Clin Exp Neuropsychol       Date:  1990-08       Impact factor: 2.475

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2.  Effects of sex and genotype in human APOE-targeted replacement mice on alcohol self-administration measured with the automated IntelliCage system before and after repeated mild traumatic brain injury.

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Review 5.  Sex, Drugs, and TBI: The Role of Sex in Substance Abuse Related to Traumatic Brain Injuries.

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