Literature DB >> 26526134

TNNI1, TNNI2 and TNNI3: Evolution, regulation, and protein structure-function relationships.

Juan-Juan Sheng1, Jian-Ping Jin2.   

Abstract

Troponin I (TnI) is the inhibitory subunit of the troponin complex in the sarcomeric thin filament of striated muscle and plays a central role in the calcium regulation of contraction and relaxation. Vertebrate TnI has evolved into three isoforms encoded by three homologous genes: TNNI1 for slow skeletal muscle TnI, TNNI2 for fast skeletal muscle TnI and TNNI3 for cardiac TnI, which are expressed under muscle type-specific and developmental regulations. To summarize the current knowledge on the TnI isoform genes and products, this review focuses on the evolution, gene regulation, posttranslational modifications, and structure-function relationship of TnI isoform proteins. Their physiological and medical significances are also discussed.
Copyright © 2015. Published by Elsevier B.V.

Entities:  

Keywords:  Cardiac and skeletal muscle; Evolution; Gene regulation; Isoform; Posttranslational modification; Troponin I

Mesh：

Substances：

Year:  2015        PMID： 26526134      PMCID： PMC5798203          DOI： 10.1016/j.gene.2015.10.052

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  133 in total

Review 1.  Isoform diversity, regulation, and functional adaptation of troponin and calponin.

Authors:  Jian-Ping Jin; Zhiling Zhang; James A Bautista
Journal:  Crit Rev Eukaryot Gene Expr       Date:  2008       Impact factor: 1.807

Review 2.  Characteristics of the human ocular surface epithelium.

Authors:  S Kinoshita; W Adachi; C Sotozono; K Nishida; N Yokoi; A J Quantock; K Okubo
Journal:  Prog Retin Eye Res       Date:  2001-09       Impact factor: 21.198

3.  Fast and slow skeletal troponin I in serum from patients with various skeletal muscle disorders: a pilot study.

Authors:  Jeremy A Simpson; Ralf Labugger; Christine Collier; Robert J Brison; Steve Iscoe; Jennifer E Van Eyk
Journal:  Clin Chem       Date:  2005-04-15       Impact factor: 8.327

Review 4.  Regulation of cardiac contractile function by troponin I phosphorylation.

Authors:  Joanne Layland; R John Solaro; Ajay M Shah
Journal:  Cardiovasc Res       Date:  2005-04-01       Impact factor: 10.787

5.  Why does troponin I have so many phosphorylation sites? Fact and fancy.

Authors:  R John Solaro; Jolanda van der Velden
Journal:  J Mol Cell Cardiol       Date:  2010-02-25       Impact factor: 5.000

6.  Cardiac troponin I as a prognostic factor in critically ill pneumonia patients in the absence of acute coronary syndrome.

Authors:  Yeon Joo Lee; Hongyeul Lee; Ji Soo Park; Se Joong Kim; Young-Jae Cho; Ho Il Yoon; Jae Ho Lee; Choon-Taek Lee; Jong Sun Park
Journal:  J Crit Care       Date:  2014-12-04       Impact factor: 3.425

7.  Impact of Type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart.

Authors:  Norbert Fülöp; Meredith M Mason; Kaushik Dutta; Peipei Wang; Amy J Davidoff; Richard B Marchase; John C Chatham
Journal:  Am J Physiol Cell Physiol       Date:  2006-11-29       Impact factor: 4.249

8.  Differential contribution of troponin I phosphorylation sites to the endothelin-modulated contractile response.

Authors:  Margaret V Westfall; Adonia M Lee; Dustin A Robinson
Journal:  J Biol Chem       Date:  2005-10-18       Impact factor: 5.157

9.  Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice.

Authors:  Yuhui Wen; Jose Renato Pinto; Aldrin V Gomes; Yuanyuan Xu; Yingcai Wang; Ying Wang; James D Potter; W Glenn L Kerrick
Journal:  J Biol Chem       Date:  2008-04-22       Impact factor: 5.157

10.  The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments.

Authors:  Agnieszka Galińska; Victoria Hatch; Roger Craig; Anne M Murphy; Jennifer E Van Eyk; C-L Albert Wang; William Lehman; D Brian Foster
Journal:  Circ Res       Date:  2009-12-24       Impact factor: 17.367
View more
  34 in total

1.  Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans.

Authors:  Deborah A Zygmunt; Neha Singhal; Mi-Lyang Kim; Megan L Cramer; Kelly E Crowe; Rui Xu; Ying Jia; Jessica Adair; Isabel Martinez-Pena Y Valenzuela; Mohammed Akaaboune; Peter White; Paulus M Janssen; Paul T Martin
Journal:  Mol Cell Biol       Date:  2017-05-02       Impact factor: 4.272

2.  Isolation and characterization of three skeletal troponin genes and association with growth-related traits in Exopalaemon carinicauda.

Authors:  Jiajia Wang; Qianqian Ge; Jitao Li; Zhao Chen; Jian Li
Journal:  Mol Biol Rep       Date:  2018-12-01       Impact factor: 2.316

Review 3.  Invertebrate troponin: Insights into the evolution and regulation of striated muscle contraction.

Authors:  Tianxin Cao; Urvashi Thongam; Jian-Ping Jin
Journal:  Arch Biochem Biophys       Date:  2019-03-27       Impact factor: 4.013

4.  High-resolution genome-wide expression analysis of single myofibers using SMART-Seq.

Authors:  Darren M Blackburn; Felicia Lazure; Aldo H Corchado; Theodore J Perkins; Hamed S Najafabadi; Vahab D Soleimani
Journal:  J Biol Chem       Date:  2019-11-21       Impact factor: 5.157

5.  Molecular alterations in oral cancer using high-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue.

Authors:  Varshasnata Mohanty; Yashwanth Subbannayya; Shankargouda Patil; Vinuth N Puttamallesh; Mohd Altaf Najar; Keshava K Datta; Sneha M Pinto; Sameera Begum; Neeta Mohanty; Samapika Routray; Riaz Abdulla; Jay Gopal Ray; David Sidransky; Harsha Gowda; T S Keshava Prasad; Aditi Chatterjee
Journal:  J Cell Commun Signal       Date:  2021-03-08       Impact factor: 5.782

Review 6.  Structural determinants of muscle thin filament cooperativity.

Authors:  Jeffrey R Moore; Stuart G Campbell; William Lehman
Journal:  Arch Biochem Biophys       Date:  2016-02-15       Impact factor: 4.013

7.  The evolutionarily conserved C-terminal peptide of troponin I is an independently configured regulatory structure to function as a myofilament Ca2+-desensitizer.

Authors:  Sienna Wong; Han-Zhong Feng; J-P Jin
Journal:  J Mol Cell Cardiol       Date:  2019-09-07       Impact factor: 5.000

8.  miR-206 enforces a slow muscle phenotype.

Authors:  Kristen K Bjorkman; Martin G Guess; Brooke C Harrison; Michael M Polmear; Angela K Peter; Leslie A Leinwand
Journal:  J Cell Sci       Date:  2020-08-11       Impact factor: 5.285

9.  Developmental programming: Adipose depot-specific transcriptional regulation by prenatal testosterone excess in a sheep model of PCOS.

Authors:  John Dou; Muraly Puttabyatappa; Vasantha Padmanabhan; Kelly M Bakulski
Journal:  Mol Cell Endocrinol       Date:  2020-12-25       Impact factor: 4.102

10.  Mandibular muscle troponin of the Florida carpenter ant Camponotus floridanus: extending our insights into invertebrate Ca2+ regulation.

Authors:  Yun Shi; Julia P Bethea; Hannah L Hetzel-Ebben; Maicon Landim-Vieira; Ross J Mayper; Regan L Williams; Lauren E Kessler; Amanda M Ruiz; Kathryn Gargiulo; Jennifer S M Rose; Grayson Platt; Jose R Pinto; Brian K Washburn; P Bryant Chase
Journal:  J Muscle Res Cell Motil       Date:  2021-07-13       Impact factor: 2.698
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.