| Literature DB >> 26525963 |
H Nandeesha1, Zachariah Bobby2, N Selvaraj3, Medha Rajappa2.
Abstract
Even though several studies have implicated the role of inflammation in the pathogenesis of hypertension and other cardiovascular disease, there are only limited studies about inflammatory markers in prehypertension. The objective of the present article was to review the role of markers like C-reactive protein, interleukin-6, tumor necrosis factor-α and sialic acid in prehypertension. An extensive literature search was made in Pubmed (http://www.ncbi.nlm.nih.gov/pubmed/) using phrases such as prehypertension, inflammation, C-reactive protein, cardiovascular disease, cytokines and sialic acid. Several investigators have reported increased inflammatory markers like C-reactive protein, interleukin-6, tumor necrosis factor-α and sialic acid in prehypertension indicating the role of inflammation in the pathogenesis of prehypertension and its complications. Elevated inflammatory markers may enhance the risk for cardiovascular disease in subjects with prehypertension.Entities:
Keywords: C-reactive protein; Cardiovascular disease; Interleukin-6; Prehypertension; Sialic acid; Tumor necrosis factor-α
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Year: 2015 PMID： 26525963 DOI： 10.1016/j.cca.2015.10.022
Source DB: PubMed Journal: Clin Chim Acta ISSN： 0009-8981 Impact factor: 3.786