Yang-nian Wei1,2, Nian-feng Li1, Xiao-yong Cai3, Bang-yu Lu3, Fei Huang3, Shi-fa Mo2, Hong-chang Zhang2, Ming-dong Wang1, Fa-sheng Wu4. 1. Xiangya Hospital of Central South University, Changsha, 410008, China. 2. Hepatobiliary Gland Surgery of Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, 530011, China. 3. Minimally Invasive Center of First Affiliated Hospital of Guangxi Medical University, Nanning, 530001, China. 4. Department of Radiotherapy, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning, 530011, China. wufasheng583@163.com.
Abstract
OBJECTIVE: To investigate the clinical effect of fast-track surgery combined with Chinese medicine treatment in devascularization operation for cirrhotic esophageal varices. METHODS:Seventy-two patients with cirrhotic esophageal varices were selected from January 2009 to June 2013, and randomly assigned to a conventional group and a fast-track group (fast-track surgery combined with Chinese medicine treatment) using a randomized digital table, 36 cases in each group. Operation and anesthesia recovery time, postoperative hospitalization and quality of life were recorded and compared between groups during the perioperative period. RESULTS: Compared with the conventional group, the fast-track group had longer operation time (253.6±46.4 min vs. 220.6±51.0 min) and anesthesia recovery time (50.5±15.9 min vs. 23.5±9.6 min; P<0.01); less bleeding (311.3±46.8 mL vs. 356.2±57.5 mL; P<0.01) and less transfusion (1932.3±106.9 mL vs. 2045.6±115.4 mL; P<0.01); as well as faster recovery of gastrointestinal function, shorter postoperative hospitalization and higher quality of life. There were no serious postoperative complications and no further bleeding occurred. CONCLUSION:Fast-track surgery combined with Chinese medicine treatment is a safe and feasible approach to accelerate the recovery of patients with cirrhotic portal hypertension in perioperative period of devascularization operation.
RCT Entities:
OBJECTIVE: To investigate the clinical effect of fast-track surgery combined with Chinese medicine treatment in devascularization operation for cirrhotic esophageal varices. METHODS: Seventy-two patients with cirrhotic esophageal varices were selected from January 2009 to June 2013, and randomly assigned to a conventional group and a fast-track group (fast-track surgery combined with Chinese medicine treatment) using a randomized digital table, 36 cases in each group. Operation and anesthesia recovery time, postoperative hospitalization and quality of life were recorded and compared between groups during the perioperative period. RESULTS: Compared with the conventional group, the fast-track group had longer operation time (253.6±46.4 min vs. 220.6±51.0 min) and anesthesia recovery time (50.5±15.9 min vs. 23.5±9.6 min; P<0.01); less bleeding (311.3±46.8 mL vs. 356.2±57.5 mL; P<0.01) and less transfusion (1932.3±106.9 mL vs. 2045.6±115.4 mL; P<0.01); as well as faster recovery of gastrointestinal function, shorter postoperative hospitalization and higher quality of life. There were no serious postoperative complications and no further bleeding occurred. CONCLUSION: Fast-track surgery combined with Chinese medicine treatment is a safe and feasible approach to accelerate the recovery of patients with cirrhotic portal hypertension in perioperative period of devascularization operation.
Entities:
Keywords:
Chinese medicine treatment; cirrhotic esophageal varices; fast-track surgery; portal-azygous disconnection; splenectomy
Authors: R J Ginsberg; P F Waters; R A Zeldin; E H Spratt; B Shandling; R M Stone; S Strasberg Journal: Ann Thorac Surg Date: 1982-09 Impact factor: 4.330