Paweł Gać1,2, Małgorzata Poręba3, Grzegorz Mazur1, Rafał Poręba1. 1. a Department of Internal Medicine , Occupational Diseases and Hypertension, Wroclaw Medical University , Wroclaw , PL , Poland . 2. b Department of Radiology and Diagnostic Imaging , 4th Military Hospital , Wroclaw , PL , Poland , and. 3. c Department of Pathophysiology , Wroclaw Medical University , Wroclaw , PL , Poland.
Abstract
CONTEXT: The impairment of the aortic mechanical features constitutes the independent predictor of all-cause and cardiovascular mortality and morbidity. OBJECTIVE: The purpose of the present research has been the determination of the influence of the environmental exposure to cigaret smoke on the aortic mechanical properties, namely, the stiffness and elasticity of aorta, in patients with essential hypertension. MATERIALS AND METHODS: The research has covered 128 people with essential hypertension: 64 nonsmokers, declaring the environmental exposure to cigaret smoke (group A) and 64 nonsmokers declaring the lack of environmental exposure to cigaret smoke selected on the case to case basis (group B). Aortic mechanical properties have been evaluated on the basis of the parameters: aortic stiffness index (AoSI), aortic strain (AoS) and aortic distensibility (AoD). RESULTS: In group A, the average values of AoSI were significantly higher, and the average values of AoS and AoD significantly lower than in group B. It has been documented that the older age and environmental exposure to cigaret smoke form independent risk factors of increasing the aortic stiffness expressed by higher values of AoSI, whereas the older age, higher pulse pressure (PP) values and environmental exposure to cigaret smoke - independent risk factors of aortic elasticity reduction expressed for the age and "passive smoking" by lower values of AoS and AoD and for PP - lower values of AoD. CONCLUSION: In patients with essential hypertension, the environmental exposure to cigaret smoke seems to result in impairment of the aortic mechanical properties.
CONTEXT: The impairment of the aortic mechanical features constitutes the independent predictor of all-cause and cardiovascular mortality and morbidity. OBJECTIVE: The purpose of the present research has been the determination of the influence of the environmental exposure to cigaret smoke on the aortic mechanical properties, namely, the stiffness and elasticity of aorta, in patients with essential hypertension. MATERIALS AND METHODS: The research has covered 128 people with essential hypertension: 64 nonsmokers, declaring the environmental exposure to cigaret smoke (group A) and 64 nonsmokers declaring the lack of environmental exposure to cigaret smoke selected on the case to case basis (group B). Aortic mechanical properties have been evaluated on the basis of the parameters: aortic stiffness index (AoSI), aortic strain (AoS) and aortic distensibility (AoD). RESULTS: In group A, the average values of AoSI were significantly higher, and the average values of AoS and AoD significantly lower than in group B. It has been documented that the older age and environmental exposure to cigaret smoke form independent risk factors of increasing the aortic stiffness expressed by higher values of AoSI, whereas the older age, higher pulse pressure (PP) values and environmental exposure to cigaret smoke - independent risk factors of aortic elasticity reduction expressed for the age and "passive smoking" by lower values of AoS and AoD and for PP - lower values of AoD. CONCLUSION: In patients with essential hypertension, the environmental exposure to cigaret smoke seems to result in impairment of the aortic mechanical properties.
Authors: Zhongjian Su; Xing Zhang; Nan Zheng; Ying Xiao; Xingzhu Liu; Yanfei Yang; Lili Deng; Yanfei Chen; Bin Li Journal: J Int Med Res Date: 2021-05 Impact factor: 1.671
Authors: Hatem Arı; Fatih Kahraman; Yasin Türker; Serdar Güler; Hasan Aydın Baş; Doğan Erdoğan Journal: Anatol J Cardiol Date: 2017-10-30 Impact factor: 1.596