| Literature DB >> 26523852 |
Xuezhen Kou1, Yu Li2, Liang Wu1, Xinghua Zhang2, Guoqiang Yang1, Wanbin Zhang1.
Abstract
A palladium-catalyzed intramolecular isoindolinone-forming aminooxygenation of alkenes with 1 atm of oxygen as oxidant is reported. A variety of functionalized alkenes and carboxylic acids can be used, and high yields were observed. Preliminary mechanistic studies revealed that the aminooxygenation products were formed through the oxidation of a C-Pd(II) species using a strong oxidant, peroxide, which is generated in situ from a Pd(OAc)2/bpy/O2/HOAc catalytic system.Entities:
Year: 2015 PMID： 26523852 DOI： 10.1021/acs.orglett.5b02703
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005