| Literature DB >> 26523829 |
Ping Liu1,2, Yongyuan Gao1, Weijin Gu1, Ziyan Shen1, Peipei Sun1,2.
Abstract
A regioselective synthesis of 3-fluorinated imidazo[1,2-a]pyridines using 1-chloromethyl-4-fluoro-1,4-diazoniabi cyclo[2.2.2]octane bis(tetrafluoroborate) (Selectfluor) as the fluorinating reagent in aqueous condition is described. In the presence of DMAP, the reaction mainly gave monofluorinated product via electrophilic fluorinated process in moderate to good yields.Entities:
Year: 2015 PMID： 26523829 DOI： 10.1021/acs.joc.5b01961
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354