Taigang Zhou1, Fei-Xian Luo1, Ming-Yu Yang1, Zhang-Jie Shi1,2. 1. Beijing National Laboratory of Molecular Sciences and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University , Beijing 100871, China. 2. State Key Laboratory of Elemento-Organic Chemistry, Nankai University , Tianjin 300071, China.
Abstract
Selective cleavage of an inert C-C bond followed by C-O/N bond formation through a long-distance aryl migration from a carbon to a nitrogen center via Ag catalysis is reported. The migration products were easily converted into γ-hydroxy amines and tetrahydroquinoline derivatives in quantitative yields. Preliminary mechanistic studies indicated a radical pathway.
Selective cleavage of an inert C-C bond followed by C-O/N bond formation through a long-distance aryl migration from a n class="Chemical">carbon to a nitrogen center via Ag catalysis is reported. The migration products were easily converted into γ-hydroxy amines and tetrahydroquinoline derivatives in quantitative yields. Preliminary mechanistic studies indicated a radical pathway.