Literature DB >> 26523262

Unusual Presentation of Cerebral Cavernous Malformation.

Won-Hyung Kim1, Dong-Jun Lim1, Jong-Il Choi1, Sung-Kon Ha1, Sang-Dae Kim1, Se-Hoon Kim1.   

Abstract

Cerebral cavernous malformations (CMs) are vascular malformations of the central nervous system, which can be detected in the absence of any clinical symptoms. Nodules and cysts with mixed signal intensity and a peripheral hemosiderin rim are considered brain magnetic resonance imaging (MRI) findings typical of CMs. A 48-year-old man was admitted to our hospital because of abnormal MRI findings without significant neurological symptoms. A cyst with an internal fluid-fluid level was found in the left basal ganglia on the initial brain MRI. We decided to observe the natural course of the asymptomatic lesion with serial MRI follow-up. On MRI at the 5-month follow-up, the cystic mass was enlarged and showed findings consistent with those of cystic CM. Surgical resection was performed and the pathological diagnosis was CM. Our experience suggests that the initial presentation of a CM can be a pure cyst and neurosurgeons should consider the likelihood of CMs in cases of cystic cerebral lesions with intracystic hemorrhage.

Entities:  

Keywords:  Cavernous malformation; Cyst; Magnetic resonance imaging

Year:  2015        PMID: 26523262      PMCID: PMC4626352          DOI: 10.7461/jcen.2015.17.3.257

Source DB:  PubMed          Journal:  J Cerebrovasc Endovasc Neurosurg        ISSN: 2234-8565


  24 in total

Review 1.  Cerebral cavernomas in the adult. Review of the literature and analysis of 72 surgically treated patients.

Authors:  Helmut Bertalanffy; Ludwig Benes; Takahito Miyazawa; Olaf Alberti; Adrian M Siegel; Ulrich Sure
Journal:  Neurosurg Rev       Date:  2002-03       Impact factor: 3.042

Review 2.  The natural history of intracranial cavernous malformations.

Authors:  Bradley A Gross; Ning Lin; Rose Du; Arthur L Day
Journal:  Neurosurg Focus       Date:  2011-06       Impact factor: 4.047

3.  Prospective hemorrhage risk of intracerebral cavernous malformations.

Authors:  K D Flemming; M J Link; T J H Christianson; R D Brown
Journal:  Neurology       Date:  2012-02-01       Impact factor: 9.910

Review 4.  Cystic cavernous angiomas.

Authors:  Shigeo Ohba; Kazuhiko Shimizu; Syunsuke Shibao; Toru Nakagawa; Hideki Murakami
Journal:  Neurosurg Rev       Date:  2010-02-20       Impact factor: 3.042

5.  Cystic cerebral cavernous angioma with dense calcification. Case report.

Authors:  R Ramina; W Ingunza; D Vonofakos
Journal:  J Neurosurg       Date:  1980-02       Impact factor: 5.115

6.  Value of gradient-echo magnetic resonance imaging in the diagnosis of familial cerebral cavernous malformation.

Authors:  Fritz-Georg Lehnhardt; Ulrich von Smekal; Benedikt Rückriem; Werner Stenzel; Michael Neveling; Wolf-Dieter Heiss; Andreas H Jacobs
Journal:  Arch Neurol       Date:  2005-04

Review 7.  Neoplastic growth of cerebral cavernous malformation presenting with impending cerebral herniation: a case report and review of the literature on de novo growth of cavernomas.

Authors:  A A Siddiqui; R Jooma
Journal:  Surg Neurol       Date:  2001-07

8.  Surgical management of brainstem cavernomas.

Authors:  M Samii; R Eghbal; G A Carvalho; C Matthies
Journal:  J Neurosurg       Date:  2001-11       Impact factor: 5.115

9.  The natural history of familial cavernous malformations: results of an ongoing study.

Authors:  J M Zabramski; T M Wascher; R F Spetzler; B Johnson; J Golfinos; B P Drayer; B Brown; D Rigamonti; G Brown
Journal:  J Neurosurg       Date:  1994-03       Impact factor: 5.115

Review 10.  Treatment of cerebral cavernous malformations: a systematic review and meta-regression analysis.

Authors:  Michiel H F Poorthuis; Catharina J M Klijn; Ale Algra; Gabriel J E Rinkel; Rustam Al-Shahi Salman
Journal:  J Neurol Neurosurg Psychiatry       Date:  2014-03-25       Impact factor: 10.154

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