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Literature DB >> 26522795

Top 10 Facts You Need to Know About Synthetic Cannabinoids: Not So Nice Spice.

Ann M Kemp¹, Molly S Clark², Thomas Dobbs³, Robert Galli⁴, Justin Sherman⁵, Robert Cox⁶.

Abstract

In April and May 2015, the state of Mississippi experienced an unprecedented outbreak of severe reactions to the drug commonly referred to as "Spice." After numerous calls to the Poison Control Center, it became clear that health care providers were largely unfamiliar with the category of synthetic cannabinoids. This review article briefly highlights cannabinoid effects, chemical characteristics, and treatment for this often-dangerous category of drugs of abuse.

Keywords: AB-CHMINACA; Excited delirium; MAB-CHIMINACA; Spice; Synthetic cannabinoids

Mesh：

Substances：

Year: 2015 PMID： 26522795 DOI： 10.1016/j.amjmed.2015.10.008

Source DB: PubMed Journal: Am J Med ISSN： 0002-9343 Impact factor: 4.965

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Cited

12 in total

1. Antidote to cannabinoid intoxication: the CB₁ receptor inverse agonist, AM251, reverses hypothermic effects of the CB₁ receptor agonist, CB-13, in mice.

Authors: Gareth Pryce; David Baker
Journal: Br J Pharmacol Date: 2017-09-20 Impact factor: 8.739

2. Alterations of the hematologic cells in synthetic cannabinoid users.

Authors: Derya Guzel; Ahmet Bulent Yazici; Esra Yazici; Atila Erol
Journal: J Clin Lab Anal Date: 2017-02-07 Impact factor: 2.352

3. In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice.

Authors: Micaela Tirri; Raffaella Arfè; Sabrine Bilel; Giorgia Corli; Beatrice Marchetti; Anna Fantinati; Fabrizio Vincenzi; Fabio De-Giorgio; Cristian Camuto; Monica Mazzarino; Mario Barbieri; Rosa Maria Gaudio; Katia Varani; Pier Andrea Borea; Francesco Botrè; Matteo Marti
Journal: Int J Mol Sci Date: 2022-07-21 Impact factor: 6.208

10. Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market.

Authors: Laith N Al-Eitan; Abdelqader S Asa'ad; AbdelKader H Battah; Hanan A Aljamal
Journal: ACS Omega Date: 2020-02-21

Top 10 Facts You Need to Know About Synthetic Cannabinoids: Not So Nice Spice.

1. Antidote to cannabinoid intoxication: the CB₁ receptor inverse agonist, AM251, reverses hypothermic effects of the CB₁ receptor agonist, CB-13, in mice.

2. Alterations of the hematologic cells in synthetic cannabinoid users.

3. In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice.

4. Trigeminal Trophic Syndrome Associated With the Use of Synthetic Marijuana.

5. Acute Rhabdomyolysis Following Synthetic Cannabinoid Ingestion.

Review 6. Novel Psychoactive Substances-Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs.

7. Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains.

8. Review of the many faces of synthetic cannabinoid toxicities.

Review 9. New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites.

10. Application of Gas Chromatography-Mass Spectrometry for the Identification and Quantitation of Three Common Synthetic Cannabinoids in Seized Materials from the Jordanian Market.