Literature DB >> 26522480

Long-term outcomes after total thyroidectomy.

Pernille Vita Fooken Jensen1, Søren Mudie Jelstrup, Preben Homøe.   

Abstract

INTRODUCTION: The aim of this study was to assess the complication rates of total thyroidectomy in a regional hospital setting in Denmark for permanent hypoparathyroidism, recurrent laryngeal nerve palsy and post-operative bleeding. Furthermore, the long-term outcomes in the management of hypoparathyroidism were investigated.
METHODS: This was a retrospective study of 114 consecutive patients undergoing total thyroidectomy due to benign thyroid disease.
RESULTS: A total of 0.9% suffered from permanent recurrent laryngeal nerve palsy, whereas temporary nerve palsy was seen in 1.8%. Post-operative bleeding occurred in 5.4%. The frequencies of temporary and permanent post-operative hypocalcaemia were 22.8% and 17.4%, respectively. Autotransplantation of parathyroid tissue was performed in 23.7%. Unintentional parathyroidectomy occurred in 8.7%. Serum ionized calcium was significantly lower preoperatively in the group that developed hypocalcaemia (p = 0.03).
CONCLUSIONS: The incidence of recurrent laryngeal nerve palsy was similar to that reported in other published studies. Post-operative bleeding was more common than in other studies. The high frequency of permanent post-operative hypocalcaemia is a cause for concern. We need to consider implementing a guideline to facilitate outfacing calcium and vitamin D supplements as an attempt to phase out was not attempted in all patients. FUNDING: not relevant. TRIAL REGISTRATION: The study was approved by the Danish Data Protection Agency, but has not been registered due to its register-based design.

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Year:  2015        PMID: 26522480

Source DB:  PubMed          Journal:  Dan Med J        ISSN: 2245-1919            Impact factor:   1.240


  9 in total

1.  Huge variations in definition and reported incidence of postsurgical hypoparathyroidism: a systematic review.

Authors:  Torben Harsløf; Lars Rolighed; Lars Rejnmark
Journal:  Endocrine       Date:  2019-02-20       Impact factor: 3.633

2.  Early discharge after total thyroidectomy: a retrospective feasibility study.

Authors:  F Tartaglia; A Giuliani; S Sorrenti; L Tromba; S Carbotta; A Maturo; G Carbotta; L De Anna; R Merola; G Livadoti; F Pelle; S Ulisse
Journal:  G Chir       Date:  2016 Nov-Dec

3.  Autofluorescence of parathyroid glands during endocrine surgery with minimally invasive technique.

Authors:  M Pastoricchio; S Bernardi; M Bortul; N de Manzini; C Dobrinja
Journal:  J Endocrinol Invest       Date:  2022-03-09       Impact factor: 4.256

4.  Association between number of parathyroid glands identified during total thyroidectomy and functional parathyroid preservation.

Authors:  Fiona Riordan; Matthew S Murphy; Linda Feeley; Patrick Sheahan
Journal:  Langenbecks Arch Surg       Date:  2021-08-18       Impact factor: 2.895

5.  Prolonged Duration of Surgery Predicts Postoperative Hypoparathyroidism among Patients Undergoing Total Thyroidectomy in a Tertiary Referral Centre.

Authors:  Emilie Sonne-Holm; Christoffer Holst Hahn
Journal:  Eur Thyroid J       Date:  2017-04-24

6.  The utility of indocyanine green (ICG) for the identification and assessment of viability of the parathyroid glands during thyroidectomy.

Authors:  S Priyanka; Shawn Thomas Sam; Grace Rebekah; Supriya Sen; Varghese Thomas; Syrpailyne Wankhar; Anish Jacob Cherian; Deepak Thomas Abraham; Mazuvanchary Jacob Paul
Journal:  Updates Surg       Date:  2021-11-02

7.  Postoperative Chronic Hypoparathyroidism and Quality of Life After Total Thyroidectomy.

Authors:  Camilla Uhre Jørgensen; Preben Homøe; Morten Dahl; Mette Friberg Hitz
Journal:  JBMR Plus       Date:  2021-03-16

8.  A Meta-Analysis of Risk Factors for Transient and Permanent Hypocalcemia After Total Thyroidectomy.

Authors:  Yuan Qin; Wei Sun; Zhihong Wang; Wenwu Dong; Liang He; Ting Zhang; Hao Zhang
Journal:  Front Oncol       Date:  2021-02-24       Impact factor: 6.244

9.  How many parathyroid glands can be identified during thyroidectomy?: Evidence-based data for medical experts.

Authors:  Elisabeth Gschwandtner; Rudolf Seemann; Claudia Bures; Lejla Preldzic; Eduard Szucsik; Michael Hermann
Journal:  Eur Surg       Date:  2017-12-13       Impact factor: 0.953

  9 in total

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