Cheng-Hsuan Wu1, Tsung-Hsien Lee2, Hsiu-Hui Chen3, Chung-I Chen4, Chun-Chia Huang4, Maw-Sheng Lee5. 1. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Obstetrics and Gynecology, Changhua Christian Hospital, Changhua, Taiwan. 2. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, Taiwan. 3. Department of Life Sciences, College of Life Sciences, National Chung Hsing University, Taichung, Taiwan; Division of Infertility Clinic, Lee Womens' Hospital, Taichung, Taiwan. 4. Division of Infertility Clinic, Lee Womens' Hospital, Taichung, Taiwan. 5. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan; Department of Obstetrics and Gynecology, Chung Shan Medical University Hospital, Taichung, Taiwan; Division of Infertility Clinic, Lee Womens' Hospital, Taichung, Taiwan. Electronic address: msleephd@gmail.com.
Abstract
OBJECTIVE: The aim of this research was to study the influence of female age on the cumulative live-birth rate of fresh and subsequent frozen cycles using vitrified blastocysts of the same cohort in hyper-responders. MATERIALS AND METHODS: This was a retrospective study of 1137 infertile women undergoing their first in vitro fertilization treatment between 2006 and 2013. The main outcome measure was cumulative live births among the fresh and all vitrified blastocyst transfers combined after the same stimulation cycle. The results were also analyzed according to age (i.e., <35 years, 35-39 years, and ≥ 40 years). RESULTS: The mean number of retrieved oocytes was 19.9 ± 8.5 oocytes. The cumulative pregnancy rate was 89.2% and the cumulative live-birth rate was 73.3%. The cumulative live-birth rate declined from 73.9% for women younger than 35 years old to 67.3% for women 35-39 years old to 57.9% for women 40 years or older. CONCLUSION: Combined fresh and vitrified blastocyst transfer cycles can result in a high cumulative live-birth rate. The cumulative live-birth rates among older women are lower than the rates among younger women when autologous oocytes are used.
OBJECTIVE: The aim of this research was to study the influence of female age on the cumulative live-birth rate of fresh and subsequent frozen cycles using vitrified blastocysts of the same cohort in hyper-responders. MATERIALS AND METHODS: This was a retrospective study of 1137 infertile women undergoing their first in vitro fertilization treatment between 2006 and 2013. The main outcome measure was cumulative live births among the fresh and all vitrified blastocyst transfers combined after the same stimulation cycle. The results were also analyzed according to age (i.e., <35 years, 35-39 years, and ≥ 40 years). RESULTS: The mean number of retrieved oocytes was 19.9 ± 8.5 oocytes. The cumulative pregnancy rate was 89.2% and the cumulative live-birth rate was 73.3%. The cumulative live-birth rate declined from 73.9% for women younger than 35 years old to 67.3% for women 35-39 years old to 57.9% for women 40 years or older. CONCLUSION: Combined fresh and vitrified blastocyst transfer cycles can result in a high cumulative live-birth rate. The cumulative live-birth rates among older women are lower than the rates among younger women when autologous oocytes are used.
Authors: Marco Milone; Loredana M Sosa Fernandez; Laura V Sosa Fernandez; Michele Manigrasso; Ugo Elmore; Giovanni D De Palma; Mario Musella; Francesco Milone Journal: Obes Surg Date: 2017-08 Impact factor: 4.129
Authors: Cheng-Hsuan Wu; Tsung-Hsien Lee; Shun-Fa Yang; Hui-Mei Tsao; Yu-Jun Chang; Chia-Hsuan Chou; Maw-Sheng Lee Journal: Int J Environ Res Public Health Date: 2019-03-19 Impact factor: 3.390
Authors: Cheng-Hsuan Wu; Shun-Fa Yang; Hui-Mei Tsao; Yu-Jun Chang; Tsung-Hsien Lee; Maw-Sheng Lee Journal: Int J Environ Res Public Health Date: 2019-03-08 Impact factor: 3.390