Literature DB >> 26519788

Stochastic descriptors in an SIR epidemic model for heterogeneous individuals in small networks.

M López-García1.   

Abstract

We continue here the work initiated in [13], and analyse an SIR epidemic model for the spread of an epidemic among the members of a small population of N individuals, defined in terms of a continuous-time Markov chain X. We propose a structure by levels and sub-levels of the state space of the process X, and present two different orders, Orders A and B, for states within each sub-level, which are related to a matrix and a scalar formalism, respectively, when developing our analysis. Stochastic descriptors regarding the length and size of an outbreak, the maximum number of individuals simultaneously infected during an outbreak, the fate of a particular individual within the population, and the number of secondary cases caused by a certain individual until he recovers, are deeply analysed. Our approach is illustrated by carrying out a set of numerical results regarding the spread of the nosocomial pathogen Methicillin-resistant Staphylococcus Aureus among the patients within an intensive care unit. In this application, our interest is in analysing the effectiveness of control strategies (the isolation of the patient initiating the outbreak and the proper room configuration of the intensive care unit) that intrinsically introduce heterogeneities among the members of the population.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Continuous-time Markov chain; Individual fate; Length and size of an outbreak; Maximum number of infected individuals; Nosocomial infections

Mesh:

Year:  2015        PMID: 26519788     DOI: 10.1016/j.mbs.2015.10.010

Source DB:  PubMed          Journal:  Math Biosci        ISSN: 0025-5564            Impact factor:   2.144


  5 in total

1.  Perturbation analysis in finite LD-QBD processes and applications to epidemic models.

Authors:  A Gómez-Corral; M López-García
Journal:  Numer Linear Algebra Appl       Date:  2018-03-05       Impact factor: 2.109

2.  Role of genetic heterogeneity in determining the epidemiological severity of H1N1 influenza.

Authors:  Narmada Sambaturu; Sumanta Mukherjee; Martín López-García; Carmen Molina-París; Gautam I Menon; Nagasuma Chandra
Journal:  PLoS Comput Biol       Date:  2018-03-21       Impact factor: 4.475

3.  Population-level mathematical modeling of antimicrobial resistance: a systematic review.

Authors:  Anna Maria Niewiadomska; Bamini Jayabalasingham; Jessica C Seidman; Lander Willem; Bryan Grenfell; David Spiro; Cecile Viboud
Journal:  BMC Med       Date:  2019-04-24       Impact factor: 8.775

4.  A geometric analysis of the SIRS epidemiological model on a homogeneous network.

Authors:  Hildeberto Jardón-Kojakhmetov; Christian Kuehn; Andrea Pugliese; Mattia Sensi
Journal:  J Math Biol       Date:  2021-09-22       Impact factor: 2.259

5.  A unified stochastic modelling framework for the spread of nosocomial infections.

Authors:  Martín López-García; Theodore Kypraios
Journal:  J R Soc Interface       Date:  2018-06       Impact factor: 4.118

  5 in total

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