Literature DB >> 26519373

Incorporating pattern identification of Chinese medicine into precision medicine: An integrative model for individualized medicine.

Jin-gen Li1, Hao Xu2.   

Abstract

On 20 January, 2015, U.S. President Obama announced an ambitious plan called "Precision Medicine (PM) Initiative", aiming to deliver genetics-based medical treatments. PM has shown a promising prospect by tailoring disease treatments and preventions to individuals. However, a predominantly genetics-based method restricts its benefit and applicability in most chronic and complex diseases. Pattern identification (PI) is one of the representative characteristics of Chinese medicine implying the concept of holism and individualized treatment. It is another classification method taking environmental, psychosocial and other individual factors into account. Integrating PI with disease diagnosis of Western medicine will provide a strong complement to genetics-based PM, thus establish an integrative model for individualized medicine. PI provides new perspectives for PM, not only in clinical practice, but also in new drug development and clinical trial design. It is for sure that the integrative approach will ultimately lead to a safer, more convenient and effective patient-centered healthcare and most patients will benefit in the era of PM.

Entities:  

Keywords:  Chinese medicine; individualized medicine; pattern identification; precision medicine; syndrome differentiation

Mesh:

Year:  2015        PMID: 26519373     DOI: 10.1007/s11655-015-2058-9

Source DB:  PubMed          Journal:  Chin J Integr Med        ISSN: 1672-0415            Impact factor:   1.978


  19 in total

1.  Syndrome classification based on manifold ranking for viral hepatitis.

Authors:  Yu-feng Zhao; Li-yun He; Bao-yan Liu; Jun Li; Feng-yi Li; Rui-li Huo; Xiang-hong Jing
Journal:  Chin J Integr Med       Date:  2013-10-30       Impact factor: 1.978

2.  Correlations among persistent viral infection, heart function and Chinese medicine syndromes in dilated cardiomyopathy patients.

Authors:  Qiang Liu; Xiao-Jia Su; Yan Yu; Yong-Lin Liu
Journal:  Chin J Integr Med       Date:  2014-07-14       Impact factor: 1.978

3.  Obama catapults patient-empowered Precision Medicine.

Authors:  Jeffrey L Fox
Journal:  Nat Biotechnol       Date:  2015-04       Impact factor: 54.908

4.  Precision medicine: the future or simply politics?

Authors:  Rita Rubin
Journal:  JAMA       Date:  2015-03-17       Impact factor: 56.272

Review 5.  Syndrome pattern and its application in parallel randomized controlled trials.

Authors:  Byung-Cheul Shin; Sina Kim; Young-Hun Cho
Journal:  Chin J Integr Med       Date:  2012-12-03       Impact factor: 1.978

6.  Blood stasis syndrome in Japan and its molecular biological analysis.

Authors:  Hirozo Goto
Journal:  Chin J Integr Med       Date:  2014-06-28       Impact factor: 1.978

7.  The diagnostic criteria of blood-stasis syndrome: considerations for standardization of pattern identification.

Authors:  Si-ming Li; Hao Xu; Ke-ji Chen
Journal:  Chin J Integr Med       Date:  2014-03-07       Impact factor: 1.978

8.  Designing clinical studies that take into account traditional East Asian medicine's systems and methods - with focus on pattern identification.

Authors:  Terje Alraek
Journal:  Chin J Integr Med       Date:  2014-05-02       Impact factor: 1.978

9.  Exploring molecular mechanism underlying Chinese medicine syndrome: a study on correlation between Chinese medicine syndrome and biomarkers for ischemic stroke.

Authors:  Lu Liu; Ying Gao; Bin Ma
Journal:  Chin J Integr Med       Date:  2013-03-25       Impact factor: 1.978

10.  Energy metabolism disorder and myocardial injury in chronic myocardial ischemia with Qi deficiency and blood stasis syndrome based on 2-DE proteomics.

Authors:  Yong Wang; Wen-Jing Chuo; Chun Li; Shu-Zhen Guo; Jian-Xin Chen; Jun-da Yu; Wei Wang
Journal:  Chin J Integr Med       Date:  2012-12-03       Impact factor: 1.978

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  5 in total

1.  Herbal Medicine for the Treatment of Anorexia in Children: A Systematic Review and Meta-Analysis.

Authors:  Boram Lee; Chan-Young Kwon; Sun Haeng Lee; Gyu Tae Chang
Journal:  Front Pharmacol       Date:  2022-04-01       Impact factor: 5.810

2.  Assessment of Intermingled Phlegm and Blood Stasis Syndrome in Coronary Heart Disease: Development of a Diagnostic Scale.

Authors:  Xuan Zhou; Xian-Tao Li; Xiao-Qi Liu; Bing Wang; Ge Fang
Journal:  Evid Based Complement Alternat Med       Date:  2018-10-24       Impact factor: 2.629

3.  Efficacy and safety of Sihogayonggolmoryeo-tang (Saikokaryukotsuboreito, Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) for post-stroke depression: A systematic review and meta-analysis.

Authors:  Chan-Young Kwon; Boram Lee; Sun-Yong Chung; Jong Woo Kim; Aesook Shin; Ye-Yong Choi; Younghee Yun; Jungtae Leem
Journal:  Sci Rep       Date:  2019-10-10       Impact factor: 4.379

Review 4.  Traditional East Asian Herbal Medicine for Post-Stroke Insomnia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Authors:  Sang-Ho Kim; Jung-Hwa Lim
Journal:  Int J Environ Res Public Health       Date:  2022-02-03       Impact factor: 3.390

Review 5.  Modern researches on Blood Stasis syndrome 1989-2015: A bibliometric analysis.

Authors:  Jiangquan Liao; Jie Wang; Yongmei Liu; Jun Li; Lian Duan; Guang Chen; Junyuan Hu
Journal:  Medicine (Baltimore)       Date:  2016-12       Impact factor: 1.817

  5 in total

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