| Literature DB >> 26519278 |
V E Tseilikman1, A I Sinitskii2, O B Tseilikman3, R V Deev2, M S Lapshin3, D A Kozochkin2.
Abstract
Under conditions of periodic exposures to anxiogenic stress, intensification of LPO in the brain cortex is a glucocorticoid-dependent process. Glucocorticoid receptor antagonist RU38486 prevented increase in monoamine oxidase B activity and content of LPO products of in brain cortex typical of anxiogenic stress. Normalization of LPO intensity under the effect of glucocorticoid receptor antagonist was associated with the correction of stress-induced disturbances.Entities:
Keywords: RU38486; glucocorticoids; lipid peroxidation; monoamine oxidase B; stress
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Year: 2015 PMID： 26519278 DOI： 10.1007/s10517-015-3060-0
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804