Literature DB >> 26519172

Visualization and Differential Analysis of Protein Expression Data Using R.

Tomé S Silva1, Nadège Richard2.   

Abstract

Data analysis is essential to derive meaningful conclusions from proteomic data. This chapter describes ways of performing common data visualization and differential analysis tasks on gel-based proteomic datasets using a freely available statistical software package (R). A workflow followed is illustrated using a synthetic dataset as example.

Keywords:  Data visualization; Differential analysis; Feature selection; Heatmap; Hypothesis testing; Independent component analysis; Multidimensional scaling; Proteomics; R; Two-dimensional gel electrophoresis

Mesh:

Substances:

Year:  2016        PMID: 26519172     DOI: 10.1007/978-1-4939-3106-4_6

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN: 1064-3745


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