Literature DB >> 26519062

Transcriptional Profiling of Candida albicans in the Host.

Kearney T W Gunsalus1, Carol A Kumamoto2.   

Abstract

Gene expression profiling has become an important tool for determining gene functions, performing phenotypic analysis, and quantifying the differential expression of individual transcripts under various conditions. Candida albicans gene expression is highly responsive to environmental conditions and rapidly adapts to various niches within the host. Here, we describe a mouse model of gastrointestinal colonization with C. albicans, the measurement of colonization in fecal pellets, and the collection of samples for transcriptional profiling. We describe how to extract and purify RNA suitable for analysis via RT-qPCR or microarray.

Entities:  

Keywords:  Candida albicans; Gene expression; Host; RNA; Transcriptional profiling

Mesh：

Year:  2016        PMID： 26519062      PMCID： PMC4750373          DOI： 10.1007/978-1-4939-3052-4_2

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  20 in total

Review 1.  Murine models of Candida gastrointestinal colonization and dissemination.

Authors:  Andrew Y Koh
Journal:  Eukaryot Cell       Date:  2013-09-13

2.  RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays.

Authors:  John C Marioni; Christopher E Mason; Shrikant M Mane; Matthew Stephens; Yoav Gilad
Journal:  Genome Res       Date:  2008-06-11       Impact factor: 9.043

3.  The transcriptional landscape of the yeast genome defined by RNA sequencing.

Authors:  Ugrappa Nagalakshmi; Zhong Wang; Karl Waern; Chong Shou; Debasish Raha; Mark Gerstein; Michael Snyder
Journal:  Science       Date:  2008-05-01       Impact factor: 47.728

4.  Mapping and quantifying mammalian transcriptomes by RNA-Seq.

Authors:  Ali Mortazavi; Brian A Williams; Kenneth McCue; Lorian Schaeffer; Barbara Wold
Journal:  Nat Methods       Date:  2008-05-30       Impact factor: 28.547

Review 5.  Inflammation and gastrointestinal Candida colonization.

Authors:  Carol A Kumamoto
Journal:  Curr Opin Microbiol       Date:  2011-07-28       Impact factor: 7.934

6.  Adaptations of Candida albicans for growth in the mammalian intestinal tract.

Authors:  Ari Rosenbach; Daniel Dignard; Jessica V Pierce; Malcolm Whiteway; Carol A Kumamoto
Journal:  Eukaryot Cell       Date:  2010-04-30

7.  Variation in Candida albicans EFG1 expression enables host-dependent changes in colonizing fungal populations.

Authors:  Jessica V Pierce; Carol A Kumamoto
Journal:  MBio       Date:  2012-07-24       Impact factor: 7.867

8.  Genome-wide analysis of Candida albicans gene expression patterns during infection of the mammalian kidney.

Authors:  Louise A Walker; Donna M Maccallum; Gwyneth Bertram; Neil A R Gow; Frank C Odds; Alistair J P Brown
Journal:  Fungal Genet Biol       Date:  2008-11-06       Impact factor: 3.495

9.  Self-regulation of Candida albicans population size during GI colonization.

Authors:  Sarah Jane White; Ari Rosenbach; Paul Lephart; Diem Nguyen; Alana Benjamin; Saul Tzipori; Malcolm Whiteway; Joan Mecsas; Carol A Kumamoto
Journal:  PLoS Pathog       Date:  2007-12       Impact factor: 6.823

10.  Passage through the mammalian gut triggers a phenotypic switch that promotes Candida albicans commensalism.

Authors:  Kalyan Pande; Changbin Chen; Suzanne M Noble
Journal:  Nat Genet       Date:  2013-07-28       Impact factor: 38.330
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  3 in total

1.  Characterization of the Effects of Candida Gastrointestinal Colonization on Clostridioides difficile Infection in a Murine Model.

Authors:  Jesús A Romo; Carol A Kumamoto
Journal:  Methods Mol Biol       Date:  2022

2.  The influence of N and S poles of static magnetic field (SMF) on Candida albicans hyphal formation and antifungal activity of amphotericin B.

Authors:  Dariusz Sztafrowski; Jakub Suchodolski; Jakub Muraszko; Karel Sigler; Anna Krasowska
Journal:  Folia Microbiol (Praha)       Date:  2019-02-20       Impact factor: 2.099

3.  New diphenylphosphane derivatives of ketoconazole are promising antifungal agents.

Authors:  Rodrigo F M de Almeida; Filipa C Santos; Krzysztof Marycz; Michalina Alicka; Anna Krasowska; Jakub Suchodolski; Jarosław J Panek; Aneta Jezierska; Radosław Starosta
Journal:  Sci Rep       Date:  2019-11-07       Impact factor: 4.379
  3 in total

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