Literature DB >> 26518972

Milk allergy is a minor cause of milk avoidance due to perceived hypersensitivity among schoolchildren in Northern Sweden.

Anna Winberg1, Christina E West1, Åsa Strinnholm2, Lisbeth Nordström1, Linnea Hedman2, Eva Rönmark2.   

Abstract

AIM: We investigated phenotypes of milk hypersensitivity among schoolchildren aged 11-12 in Northern Sweden.
METHODS: In a population-based cohort, 1824 (98%) children aged 11-12 participated in a questionnaire survey, skin prick testing, interviews on food hypersensitivity and assessment of body mass index (BMI). Of the 265 children reporting milk hypersensitivity, milk avoidance and no coeliac disease, 236 (89%) participated in a structured interview and blood samples for analyses of milk-specific Immunoglobulin E. The children were then categorised into milk hypersensitivity phenotypes according to preset criteria.
RESULTS: In all, 14.5% reported milk hypersensitivity. Of these, 3% were categorised as current milk allergy, 23% as outgrown milk allergy, 40% as probable lactose intolerance and 11% as nondefinable. Furthermore, 23% had discontinued their elimination diet. Milk allergy was associated with other atopic disorders and lower BMI, with an odds ratio of 0.82 and 95% confidence interval of 0.80-0.98. Only 2% had previously undergone an oral challenge.
CONCLUSION: The most common symptom phenotypes among Swedish children aged 11-12 with self-reported milk hypersensitivity and milk avoidance were probable intolerance and outgrown milk allergy, while current milk allergy was uncommon. Children with milk allergy had a lower BMI and most lacked a challenge-proven diagnosis. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  Body mass index; Child; Cow's milk; Epidemiology; Food allergy

Mesh:

Substances:

Year:  2015        PMID: 26518972     DOI: 10.1111/apa.13253

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  2 in total

1.  Health Related Quality of Life among schoolchildren aged 12-13 years in relation to food hypersensitivity phenotypes: a population-based study.

Authors:  Åsa Strinnholm; Linnéa Hedman; Anna Winberg; Sven-Arne Jansson; Viveca Lindh; Eva Rönmark
Journal:  Clin Transl Allergy       Date:  2017-07-03       Impact factor: 5.871

2.  Milk-Related Symptoms and Immunoglobulin E Reactivity in Swedish Children from Early Life to Adolescence.

Authors:  Jennifer L P Protudjer; Ola Olén; Mirja Vetander; Inger Kull; Erik Melén; Marianne van Hage; Magnus Wickman; Anna Bergström
Journal:  Nutrients       Date:  2018-05-21       Impact factor: 5.717

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.