Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Mild cognitive impairment: an update in Parkinson's disease and lessons learned from Alzheimer's disease.

Literature DB >> 26517759

Mild cognitive impairment: an update in Parkinson's disease and lessons learned from Alzheimer's disease.

Jennifer G Goldman¹, Neelum T Aggarwal², Cynthia D Schroeder³.

Abstract

Cognitive dysfunction is an important focus of research in Parkinson's disease (PD) and Alzheimer's disease (AD). While the concept of amnestic mild cognitive impairment (MCI) as a prodrome to AD has been recognized for many years, the construct of MCI in PD is a relative newcomer with recent development of diagnostic criteria, biomarker research programs and treatment trials. Controversies and challenges, however, regarding PD-MCI's definition, application, heterogeneity and different trajectories have arisen. This review will highlight current research advances and challenges in PD-MCI. Furthermore, lessons from the AD field, which has witnessed an evolution in MCI/AD definitions, relevant advances in biomarker research and development of disease-modifying and targeted therapeutic trials will be discussed.

Entities: CellLine Chemical Disease Gene Species

Keywords: Alzheimer's disease; Parkinson's disease; amnestic; biomarker; cognitive; dementia; diagnostic criteria; executive function; mild cognitive impairment; nonamnestic

Mesh：

Substances：
Biomarkers

Year: 2015 PMID： 26517759 PMCID： PMC4968199 DOI： 10.2217/nmt.15.34

Source DB: PubMed Journal: Neurodegener Dis Manag ISSN： 1758-2024

106 in total

1. Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia.

Authors: Liana G Apostolova; Mona Beyer; Amity E Green; Kristy S Hwang; Jonathan H Morra; Yi-Yu Chou; Christina Avedissian; Dag Aarsland; Carmen C Janvin; Jan P Larsen; Jeffrey L Cummings; Paul M Thompson
Journal: Mov Disord Date: 2010-04-30 Impact factor: 10.338

2. Insulin and insulin-like growth factor expression and function deteriorate with progression of Alzheimer's disease: link to brain reductions in acetylcholine.

Authors: Enrique J Rivera; Alison Goldin; Noah Fulmer; Rose Tavares; Jack R Wands; Suzanne M de la Monte
Journal: J Alzheimers Dis Date: 2005-12 Impact factor: 4.472

3. Characterizing mild cognitive impairment in Parkinson's disease.

Authors: John C Dalrymple-Alford; Leslie Livingston; Michael R MacAskill; Charlotte Graham; Tracy R Melzer; Richard J Porter; Richard Watts; Tim J Anderson
Journal: Mov Disord Date: 2011-02-01 Impact factor: 10.338

Review 4. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics.

Authors: Dennis J Selkoe; Dale Schenk
Journal: Annu Rev Pharmacol Toxicol Date: 2002-01-10 Impact factor: 13.820

5. Heterogeneous neuropathological findings in Parkinson's disease with mild cognitive impairment.

Authors: Charles H Adler; John N Caviness; Marwan N Sabbagh; Holly A Shill; Donald J Connor; Lucia Sue; Virgilio G H Evidente; Erika Driver-Dunckley; Thomas G Beach
Journal: Acta Neuropathol Date: 2010-09-14 Impact factor: 17.088

6. Cognitive complaints in Parkinson's disease: its relationship with objective cognitive decline.

Authors: Kathy Dujardin; Alain Duhamel; Marie Delliaux; Catherine Thomas-Antérion; Alain Destée; Luc Defebvre
Journal: J Neurol Date: 2009-08-19 Impact factor: 4.849

7. Relation of neuropathology to cognition in persons without cognitive impairment.

Authors: David A Bennett; Robert S Wilson; Patricia A Boyle; Aron S Buchman; Julie A Schneider
Journal: Ann Neurol Date: 2012-10 Impact factor: 10.422

8. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

Authors: J C Lambert; C A Ibrahim-Verbaas; D Harold; A C Naj; R Sims; C Bellenguez; A L DeStafano; J C Bis; G W Beecham; B Grenier-Boley; G Russo; T A Thorton-Wells; N Jones; A V Smith; V Chouraki; C Thomas; M A Ikram; D Zelenika; B N Vardarajan; Y Kamatani; C F Lin; A Gerrish; H Schmidt; B Kunkle; M L Dunstan; A Ruiz; M T Bihoreau; S H Choi; C Reitz; F Pasquier; C Cruchaga; D Craig; N Amin; C Berr; O L Lopez; P L De Jager; V Deramecourt; J A Johnston; D Evans; S Lovestone; L Letenneur; F J Morón; D C Rubinsztein; G Eiriksdottir; K Sleegers; A M Goate; N Fiévet; M W Huentelman; M Gill; K Brown; M I Kamboh; L Keller; P Barberger-Gateau; B McGuiness; E B Larson; R Green; A J Myers; C Dufouil; S Todd; D Wallon; S Love; E Rogaeva; J Gallacher; P St George-Hyslop; J Clarimon; A Lleo; A Bayer; D W Tsuang; L Yu; M Tsolaki; P Bossù; G Spalletta; P Proitsi; J Collinge; S Sorbi; F Sanchez-Garcia; N C Fox; J Hardy; M C Deniz Naranjo; P Bosco; R Clarke; C Brayne; D Galimberti; M Mancuso; F Matthews; S Moebus; P Mecocci; M Del Zompo; W Maier; H Hampel; A Pilotto; M Bullido; F Panza; P Caffarra; B Nacmias; J R Gilbert; M Mayhaus; L Lannefelt; H Hakonarson; S Pichler; M M Carrasquillo; M Ingelsson; D Beekly; V Alvarez; F Zou; O Valladares; S G Younkin; E Coto; K L Hamilton-Nelson; W Gu; C Razquin; P Pastor; I Mateo; M J Owen; K M Faber; P V Jonsson; O Combarros; M C O'Donovan; L B Cantwell; H Soininen; D Blacker; S Mead; T H Mosley; D A Bennett; T B Harris; L Fratiglioni; C Holmes; R F de Bruijn; P Passmore; T J Montine; K Bettens; J I Rotter; A Brice; K Morgan; T M Foroud; W A Kukull; D Hannequin; J F Powell; M A Nalls; K Ritchie; K L Lunetta; J S Kauwe; E Boerwinkle; M Riemenschneider; M Boada; M Hiltuenen; E R Martin; R Schmidt; D Rujescu; L S Wang; J F Dartigues; R Mayeux; C Tzourio; A Hofman; M M Nöthen; C Graff; B M Psaty; L Jones; J L Haines; P A Holmans; M Lathrop; M A Pericak-Vance; L J Launer; L A Farrer; C M van Duijn; C Van Broeckhoven; V Moskvina; S Seshadri; J Williams; G D Schellenberg; P Amouyel
Journal: Nat Genet Date: 2013-10-27 Impact factor: 38.330

Review 9. Magnetic resonance imaging: a biomarker for cognitive impairment in Parkinson's disease?

Authors: Gordon W Duncan; Michael J Firbank; John T O'Brien; David J Burn
Journal: Mov Disord Date: 2013-02-28 Impact factor: 10.338

Review 10. Evolution of cognitive dysfunction in an incident Parkinson's disease cohort.

Authors: C H Williams-Gray; T Foltynie; C E G Brayne; T W Robbins; R A Barker
Journal: Brain Date: 2007-05-29 Impact factor: 13.501

9 in total

Review 1. Fragile X-associated tremor/ataxia syndrome: phenotypic comparisons with other movement disorders.

Authors: Erin E Robertson; Deborah A Hall; Andrew R McAsey; Joan A O'Keefe
Journal: Clin Neuropsychol Date: 2016-08 Impact factor: 3.535

2. No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson's disease in nine ADHD candidate SNPs.

Authors: Julia M Geissler; Marcel Romanos; Manfred Gerlach; Daniela Berg; Claudia Schulte
Journal: Atten Defic Hyperact Disord Date: 2017-02-07

3. Initial elevations in glutamate and dopamine neurotransmission decline with age, as does exploratory behavior, in LRRK2 G2019S knock-in mice.

Authors: Mattia Volta; Dayne A Beccano-Kelly; Sarah A Paschall; Stefano Cataldi; Sarah E MacIsaac; Matthew J Farrer; Austen J Milnerwood; Naila Kuhlmann; Chelsie A Kadgien; Igor Tatarnikov; Jesse Fox; Jaskaran Khinda; Emma Mitchell; Sabrina Bergeron; Heather Melrose
Journal: Elife Date: 2017-09-20 Impact factor: 8.140

4. The interactions of dopamine and oxidative damage in the striatum of patients with neurodegenerative diseases.

Authors: Huifangjie Li; Pengfei Yang; William Knight; Yingqiu Guo; Joel S Perlmutter; Tammie L S Benzinger; John C Morris; Jinbin Xu
Journal: J Neurochem Date: 2019-11-04 Impact factor: 5.372

5. Enhancement of Executive Functions but Not Memory by Multidomain Group Cognitive Training in Patients with Parkinson's Disease and Mild Cognitive Impairment: A Multicenter Randomized Controlled Trial.

Authors: Elke Kalbe; Ann-Kristin Folkerts; Anja Ophey; Carsten Eggers; Saskia Elben; Karina Dimenshteyn; Patricia Sulzer; Claudia Schulte; Nele Schmidt; Christian Schlenstedt; Daniela Berg; Karsten Witt; Lars Wojtecki; Inga Liepelt-Scarfone
Journal: Parkinsons Dis Date: 2020-11-30

9. Is the Random Forest Algorithm Suitable for Predicting Parkinson's Disease with Mild Cognitive Impairment out of Parkinson's Disease with Normal Cognition?

Authors: Haewon Byeon
Journal: Int J Environ Res Public Health Date: 2020-04-10 Impact factor: 3.390