Literature DB >> 26517194

ATM serine-1981 phosphorylation is a plausible biomarker.

Christopher J Bakkenist1, Jan H Beumer2,3, John C Schmitz3.   

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Year:  2015        PMID： 26517194      PMCID： PMC4825586          DOI： 10.1080/15384101.2015.1084205

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

Review 1.  Biomarkers and surrogate endpoints: preferred definitions and conceptual framework.

Authors: 
Journal:  Clin Pharmacol Ther       Date:  2001-03       Impact factor: 6.875

2.  Guidelines for the development and incorporation of biomarker studies in early clinical trials of novel agents.

Authors:  Janet E Dancey; Kevin K Dobbin; Susan Groshen; J Milburn Jessup; Andrew H Hruszkewycz; Maria Koehler; Ralph Parchment; Mark J Ratain; Lalitha K Shankar; Walter M Stadler; Lawrence D True; Amy Gravell; Michael R Grever
Journal:  Clin Cancer Res       Date:  2010-03-09       Impact factor: 12.531

3.  DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation.

Authors:  Christopher J Bakkenist; Michael B Kastan
Journal:  Nature       Date:  2003-01-30       Impact factor: 49.962

4.  Irreversible chromosome damage accumulates rapidly in the absence of ATM kinase activity.

Authors:  Jason S White; Serah Choi; Christopher J Bakkenist
Journal:  Cell Cycle       Date:  2008-03-18       Impact factor: 4.534

5.  ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling.

Authors:  Thomas Stiff; Sarah A Walker; Karen Cerosaletti; Aaron A Goodarzi; Eva Petermann; Pat Concannon; Mark O'Driscoll; Penny A Jeggo
Journal:  EMBO J       Date:  2006-11-23       Impact factor: 11.598

6.  A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells.

Authors:  Christopher J Bakkenist; R Kenneth Czambel; Pamela A Hershberger; Hussein Tawbi; Jan H Beumer; John C Schmitz
Journal:  Oncoscience       Date:  2015-05-14

7.  Radiation therapy induces the DNA damage response in peripheral blood.

Authors:  Christopher J Bakkenist; R Kenneth Czambel; David A Clump; Joel S Greenberger; Jan H Beumer; John C Schmitz
Journal:  Oncotarget       Date:  2013-08
  7 in total
  4 in total

1.  Phase I study of veliparib in combination with gemcitabine.

Authors:  Ronald Stoller; John C Schmitz; Fei Ding; Shannon Puhalla; Chandra P Belani; Leonard Appleman; Yan Lin; Yixing Jiang; Salah Almokadem; Daniel Petro; Julianne Holleran; Brian F Kiesel; R Ken Czambel; Benedito A Carneiro; Emmanuel Kontopodis; Pamela A Hershberger; Madani Rachid; Alice Chen; Edward Chu; Jan H Beumer
Journal:  Cancer Chemother Pharmacol       Date:  2017-08-02       Impact factor: 3.333

2.  Quantitative analysis of ATM phosphorylation in lymphocytes.

Authors:  Christopher J Bakkenist; R Kenneth Czambel; Yan Lin; Nathan A Yates; Xuemei Zeng; Jeffery Shogan; John C Schmitz
Journal:  DNA Repair (Amst)       Date:  2019-06-04

3.  SOCS1 regulates senescence and ferroptosis by modulating the expression of p53 target genes.

Authors:  Emmanuelle Saint-Germain; Lian Mignacca; Mathieu Vernier; Diwakar Bobbala; Subburaj Ilangumaran; Gerardo Ferbeyre
Journal:  Aging (Albany NY)       Date:  2017-10-28       Impact factor: 5.682

4.  The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.

Authors:  Stephen T Durant; Li Zheng; Yingchun Wang; Kan Chen; Lingli Zhang; Tianwei Zhang; Zhenfan Yang; Lucy Riches; Antonio G Trinidad; Jacqueline H L Fok; Tom Hunt; Kurt G Pike; Joanne Wilson; Aaron Smith; Nicola Colclough; Venkatesh Pilla Reddy; Andrew Sykes; Annika Janefeldt; Peter Johnström; Katarina Varnäs; Akihiro Takano; Stephanie Ling; Jonathan Orme; Jonathan Stott; Caroline Roberts; Ian Barrett; Gemma Jones; Martine Roudier; Andrew Pierce; Jasmine Allen; Jenna Kahn; Amrita Sule; Jeremy Karlin; Anna Cronin; Melissa Chapman; Kristoffer Valerie; Ruth Illingworth; Martin Pass
Journal:  Sci Adv       Date:  2018-06-20       Impact factor: 14.136
  4 in total

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