INTRODUCTION: The mosquito Aedes aegypti has evolved resistance to pyrethroid insecticides. The present study evaluated Ae. aegypti from Goiânia for the resistant phenotype and for mutations associated with resistance. METHODS: Insecticide dose-response bioassays were conducted on mosquitoes descended from field-collected eggs, and polymerase chain reaction (PCR) was used to genotype 90 individuals at sites implicated in pyrethroid resistance. RESULTS: All mosquito populations displayed high levels of resistance to deltamethrin, as well as high frequencies of the 1016Ile kdr and 1534Cys kdrmutations. CONCLUSIONS: Aedes aegypti populations in the Goiânia area are highly resistant to deltamethrin, presumably due to high frequencies of kdr(knockdown-resistance) mutations.
INTRODUCTION: The mosquito Aedes aegypti has evolved resistance to pyrethroid insecticides. The present study evaluated Ae. aegypti from Goiânia for the resistant phenotype and for mutations associated with resistance. METHODS: Insecticide dose-response bioassays were conducted on mosquitoes descended from field-collected eggs, and polymerase chain reaction (PCR) was used to genotype 90 individuals at sites implicated in pyrethroid resistance. RESULTS: All mosquito populations displayed high levels of resistance to deltamethrin, as well as high frequencies of the 1016Ile kdr and 1534Cys kdrmutations. CONCLUSIONS:Aedes aegypti populations in the Goiânia area are highly resistant to deltamethrin, presumably due to high frequencies of kdr(knockdown-resistance) mutations.
Authors: Khalid Haddi; Hudson V V Tomé; Yuzhe Du; Wilson R Valbon; Yoshiko Nomura; Gustavo F Martins; Ke Dong; Eugênio E Oliveira Journal: Sci Rep Date: 2017-04-19 Impact factor: 4.379
Authors: Maria de Lourdes Macoris; Ademir Jesus Martins; Maria Teresa Macoris Andrighetti; José Bento Pereira Lima; Denise Valle Journal: PLoS Negl Trop Dis Date: 2018-03-30
Authors: Farah Z Vera-Maloof; Karla Saavedra-Rodriguez; Rosa P Penilla-Navarro; Americo D Rodriguez-Ramirez; Felipe Dzul; Pablo Manrique-Saide; William C Black Journal: PLoS Negl Trop Dis Date: 2020-03-16