Literature DB >> 26516508

Case studies illustrating the management of trigeminal neuropathic pain using topical 5% lidocaine plasters.

Nadine Khawaja1, Zehra Yilmaz1, Tara Renton1.   

Abstract

UNLABELLED: Chronic trigeminal pain, with its severe related functional problems, is difficult to treat. Treatment is often empirically based on medications used for other chronic pain conditions. Systemic sodium channel and calcium channel blocking agents may cause a multitude of complications that are often poorly tolerated by the patient. AIM: The aim of this case report was to assess the efficacy of topical 5% lidocaine plasters in reducing pain and reducing adjuvant medication in patients with orofacial neuropathic pain.
METHOD: Fourteen patients with chronic orofacial pain conditions referred to the oral surgery department were instructed to wear 5% lidocaine plasters for 12 hours each day over the painful area. The conditions included post-surgical neuropathy (n = 10), multiple sclerosis-related pain (n = 1), persistent idiopathic facial pain (n = 1), Ramsay Hunt syndrome (post-herpetic neuralgia, n = 1) and trigeminal neuralgia (n = 1). Data were collected on patient demographics, pain levels and medication.
RESULTS: Pain levels improved in 12 out of 14 patients. Nine patients had a reduction in adjuvant medication, two of whom completely stopped adjuvant treatment.
CONCLUSION: This case series demonstrates that of the use of 5% lidocaine plasters may play a useful role in the management of chronic trigeminal pain. A suggested novel approach for the management of orofacial pain, for clinicians, is presented. SUMMARY POINTS: Management of chronic orofacial pain continues to be a major challenge to the clinician.Patients are often placed on a multitude of medications in an attempt to alleviate pain without success.Topical 5% lidocaine plasters, currently used for the management of post-herpetic neuralgia, offer the option of locally targeting trigeminal pain without the multiple side-effects of systemic medication.This case series demonstrates that lidocaine plasters decrease verbal pain scores in extraoral, trigeminal and neuropathic pain, and reduce the use of other neuromodulatory agents in some, but not all, patients.The plasters should be considered as a useful adjuvant in the management of pain in these patients.

Entities:  

Keywords:  Chronic; lidocaine; neuropathic; pain; topical; trigeminal

Year:  2013        PMID: 26516508      PMCID: PMC4590123          DOI: 10.1177/2049463713483459

Source DB:  PubMed          Journal:  Br J Pain        ISSN: 2049-4637


  19 in total

Review 1.  Practice parameter: treatment of postherpetic neuralgia: an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology.

Authors:  R M Dubinsky; H Kabbani; Z El-Chami; C Boutwell; H Ali
Journal:  Neurology       Date:  2004-09-28       Impact factor: 9.910

Review 2.  Chronic facial pain: a multidisciplinary problem.

Authors:  G Madland; C Feinmann
Journal:  J Neurol Neurosurg Psychiatry       Date:  2001-12       Impact factor: 10.154

Review 3.  Topical pain management with the 5% lidocaine medicated plaster--a review.

Authors:  Gérard Mick; Gerardo Correa-Illanes
Journal:  Curr Med Res Opin       Date:  2012-05-24       Impact factor: 2.580

4.  Towards a new taxonomy of idiopathic orofacial pain.

Authors:  Alain Woda; Stéphanie Tubert-Jeannin; Didier Bouhassira; Nadine Attal; Bernard Fleiter; Jean-Paul Goulet; Christelle Gremeau-Richard; Marie Louise Navez; Pascale Picard; Paul Pionchon; Eliane Albuisson
Journal:  Pain       Date:  2005-08       Impact factor: 6.961

5.  Pharmacokinetics and safety of continuously applied lidocaine patches 5%.

Authors:  Arnold R Gammaitoni; Nancy A Alvarez; Bradley S Galer
Journal:  Am J Health Syst Pharm       Date:  2002-11-15       Impact factor: 2.637

6.  Managing iatrogenic trigeminal nerve injury: a case series and review of the literature.

Authors:  T Renton; Z Yilmaz
Journal:  Int J Oral Maxillofac Surg       Date:  2012-02-10       Impact factor: 2.789

7.  An update on pain.

Authors:  T Renton
Journal:  Br Dent J       Date:  2008-03-22       Impact factor: 1.626

8.  Case studies on implant removal influencing the resolution of inferior alveolar nerve injury.

Authors:  N Khawaja; T Renton
Journal:  Br Dent J       Date:  2009-04-11       Impact factor: 1.626

Review 9.  Evidence-based approach to the medical management of trigeminal neuralgia.

Authors:  T P Jorns; J M Zakrzewska
Journal:  Br J Neurosurg       Date:  2007-06       Impact factor: 1.596

10.  Temporomandibular disorders: A position paper of the International College of Cranio-Mandibular Orthopedics (ICCMO).

Authors:  Barry C Cooper
Journal:  Cranio       Date:  2011-07       Impact factor: 2.020

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  4 in total

Review 1.  An update on the causes, assessment and management of third division sensory trigeminal neuropathies.

Authors:  E Carter; Z Yilmaz; M Devine; T Renton
Journal:  Br Dent J       Date:  2016-06-24       Impact factor: 1.626

Review 2.  Trigeminal Traumatic Neuroma: a Comprehensive Review of the Literature Based On a Rare Case.

Authors:  Davis C Thomas; Saranya Devatha Mallareddy; Jeffrey P Okeson; Josna Thankachan; Priyanka Kodaganallur Pitchumani; Reshmy Chellam Pichammal
Journal:  Curr Pain Headache Rep       Date:  2022-02-04

3.  Bilateral intraoral traumatic neuroma: Case report of a diagnostic challenge.

Authors:  Davis C Thomas; Rangarajan Vedantham; Nishanthini Annamalai; Priyanka Kodaganallur Pitchumani
Journal:  J Indian Prosthodont Soc       Date:  2021 Oct-Dec

4.  The Effect of Intravenous Lidocaine on Trigeminal Neuralgia: A Randomized Double Blind Placebo Controlled Trial.

Authors:  Evmorfia Stavropoulou; Erifili Argyra; Panagiotis Zis; Athina Vadalouca; Ioanna Siafaka
Journal:  ISRN Pain       Date:  2014-03-10
  4 in total

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