Literature DB >> 26515735

Management of Medication-Related Osteonecrosis of the Jaw.

William Bradford Williams1, Felice O'Ryan2.   

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) primarily involves patients receiving intravenous bisphosphonates for treatment of skeletal-related malignancies, oral bisphosphonates, and denosumab. There is no consensus regarding the clinical management of MRONJ. Successful treatment may be that which results in a cure, with complete mucosal coverage and elimination of disease, or that which improves the quality of life without a cure (palliation). Helping patients to understand the chronicity and potential progression of the disease is essential to a satisfactory outcome. This review aims to share our treatment approach to patients with MRONJ. Treatment can be divided into medical and surgical therapies.
Copyright © 2015 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  BRONJ; Bisphosphonate; Denosumab; MRONJ; Maxillofacial surgery; Oral surgery

Mesh:

Substances:

Year:  2015        PMID: 26515735     DOI: 10.1016/j.coms.2015.06.007

Source DB:  PubMed          Journal:  Oral Maxillofac Surg Clin North Am        ISSN: 1042-3699            Impact factor:   2.802


  7 in total

1.  Combined Approach to Treat Medication-Related Osteonecrosis of the Jaws.

Authors:  Elisabetta Merigo; Luigi Cella; Aldo Oppici; Maria Cristina Arbasi; Fabio Clini; Matteo Fontana; Carlo Fornaini
Journal:  J Lasers Med Sci       Date:  2018-03-20

2.  Low-dose methotrexate in rheumatoid arthritis: a potential risk factor for bisphosphonate-induced osteonecrosis of the jaw.

Authors:  Paul C Mathai; Neelam N Andrade; Neha Aggarwal; Shibani Nerurkar; Prathmesh Kapoor
Journal:  Oral Maxillofac Surg       Date:  2018-03-05

3.  Osteonecrosis of the jaw in patients transitioning from bisphosphonates to denosumab treatment for osteoporosis.

Authors:  P J Voss; D Steybe; P Poxleitner; R Schmelzeisen; C Munzenmayer; H Fuellgraf; A Stricker; W Semper-Hogg
Journal:  Odontology       Date:  2018-04-30       Impact factor: 2.634

Review 4.  Bisphosphonate-Induced Osteonecrosis of the Jaws (BIONJ).

Authors:  Madhumati Singh; Giriraj Sandeep Gonegandla
Journal:  J Maxillofac Oral Surg       Date:  2019-04-08

5.  Treatment of medication-related osteonecrosis of the jaws (MRONJ) with ultrasonic piezoelectric bone surgery. A case series of 20 treated sites.

Authors:  Cornelio Blus; Giulio Giannelli; Serge Szmukler-Moncler; Germano Orru
Journal:  Oral Maxillofac Surg       Date:  2016-12-06

Review 6.  Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (1), role of imaging in drug-related osteonecrosis of the jaw: An up-to-date review (secondary publication).

Authors:  Makoto Tsuchimochi; Tohru Kurabayashi
Journal:  Jpn Dent Sci Rev       Date:  2019-01-17

7.  Human amniotic membrane: an improvement in the treatment of Medication-related osteonecrosis of the jaw (MRONJ)? A case-control study.

Authors:  Mirko Ragazzo; Matteo Val; Giulia Montagner; Diletta Trojan; Stefano Fusetti; Luca Guarda Nardini
Journal:  Cell Tissue Bank       Date:  2021-04-15       Impact factor: 1.522

  7 in total

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