| Literature DB >> 26515735 |
William Bradford Williams1, Felice O'Ryan2.
Abstract
Medication-related osteonecrosis of the jaw (MRONJ) primarily involves patients receiving intravenous bisphosphonates for treatment of skeletal-related malignancies, oral bisphosphonates, and denosumab. There is no consensus regarding the clinical management of MRONJ. Successful treatment may be that which results in a cure, with complete mucosal coverage and elimination of disease, or that which improves the quality of life without a cure (palliation). Helping patients to understand the chronicity and potential progression of the disease is essential to a satisfactory outcome. This review aims to share our treatment approach to patients with MRONJ. Treatment can be divided into medical and surgical therapies.Entities:
Keywords: BRONJ; Bisphosphonate; Denosumab; MRONJ; Maxillofacial surgery; Oral surgery
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Year: 2015 PMID: 26515735 DOI: 10.1016/j.coms.2015.06.007
Source DB: PubMed Journal: Oral Maxillofac Surg Clin North Am ISSN: 1042-3699 Impact factor: 2.802