BACKGROUND: Endoscopic approaches have been adopted as an alternative to craniofacial resection in the surgical management of olfactory neuroblastoma. METHODS: We conducted a systematic review and meta-analysis using MEDLINE, EMBASE, Cochrane, and CINAHL (2000-2014) to compare outcomes for open versus endoscopic approaches. RESULTS: Thirty-six studies containing 609 patients were included. Meta-analysis of (a) all patients, (b) Kadish C/D only, and (c) Hyams III/IV only, failed to show a difference in locoregional control and metastasis-free survival between approaches. However, endoscopic approaches were associated with improved overall survival (OS) for all 3 groups (p = .001, .04, and .001, respectively), and higher disease-specific survival (DSS) for all patients (p = .004) and Hyams III/IV only (p = .002). CONCLUSION: The current study suggests that endoscopic approaches have comparable control rates to open approaches for olfactory neuroblastoma.
BACKGROUND: Endoscopic approaches have been adopted as an alternative to craniofacial resection in the surgical management of olfactory neuroblastoma. METHODS: We conducted a systematic review and meta-analysis using MEDLINE, EMBASE, Cochrane, and CINAHL (2000-2014) to compare outcomes for open versus endoscopic approaches. RESULTS: Thirty-six studies containing 609 patients were included. Meta-analysis of (a) all patients, (b) Kadish C/D only, and (c) Hyams III/IV only, failed to show a difference in locoregional control and metastasis-free survival between approaches. However, endoscopic approaches were associated with improved overall survival (OS) for all 3 groups (p = .001, .04, and .001, respectively), and higher disease-specific survival (DSS) for all patients (p = .004) and Hyams III/IV only (p = .002). CONCLUSION: The current study suggests that endoscopic approaches have comparable control rates to open approaches for olfactory neuroblastoma.
Authors: Terence S Fu; Eric Monteiro; Ian Witterick; Allan Vescan; Gelareh Zadeh; Fred Gentili; John R de Almeida Journal: J Neurol Surg B Skull Base Date: 2017-06-30
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Authors: Robbie S R Woods; Thavakumar Subramaniam; Mary Leader; Rory McConn-Walsh; James Paul O'Neill; Peter D Lacy Journal: J Neurol Surg B Skull Base Date: 2017-11-01
Authors: Khodayar Goshtasbi; Jack L Birkenbeuel; Mehdi Abouzari; Brandon M Lehrich; Tyler M Yasaka; Arash Abiri; Ethan G Muhonen; Frank P K Hsu; Edward C Kuan Journal: Am J Rhinol Allergy Date: 2020-10-29 Impact factor: 2.467