Literature DB >> 26514404

Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery.

Vipul Agarwal1, Priyanka Toshniwal, Natalie E Smith, Nicole M Smith, Binbin Li, Tristan D Clemons, Lindsay T Byrne, Foteini Kakulas, Fiona M Wood, Mark Fear, Ben Corry, K Swaminathan Iyer.   

Abstract

Intracellular delivery of M6P/IGFII receptor inhibitors exhibits better efficacy than extracellular inhibitors to regulate TGFβ1 mediated upregulation of profibrotic marker, collagen I.

Entities:  

Year:  2015        PMID: 26514404     DOI: 10.1039/c5cc06826f

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  6 in total

1.  General Linker Diversification Approach to Bivalent Ligand Assembly: Generation of an Array of Ligands for the Cation-Independent Mannose 6-Phosphate Receptor.

Authors:  Xiang Fei; Megan E Zavorka; Guillaume Malik; Christopher M Connelly; Richard G MacDonald; David B Berkowitz
Journal:  Org Lett       Date:  2017-07-28       Impact factor: 6.005

2.  Dual-Functional Titanium(IV) Immobilized Metal Affinity Chromatography Approach for Enabling Large-Scale Profiling of Protein Mannose-6-Phosphate Glycosylation and Revealing Its Predominant Substrates.

Authors:  Junfeng Huang; Jing Dong; Xudong Shi; Zhengwei Chen; Yusi Cui; Xiaoyan Liu; Mingliang Ye; Lingjun Li
Journal:  Anal Chem       Date:  2019-08-22       Impact factor: 6.986

3.  Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins.

Authors:  Yaxian Zhou; Peng Teng; Nathan T Montgomery; Xiaolei Li; Weiping Tang
Journal:  ACS Cent Sci       Date:  2021-03-04       Impact factor: 14.553

4.  Surface refined AuQuercetin nanoconjugate stimulates dermal cell migration: possible implication in wound healing.

Authors:  Madhyastha H; Halder S; Queen Intan N; Madhyastha R; Mohanapriya A; Sudhakaran R; Sajitha L S; Banerjee K; Bethasiwi P; Daima H; Navya P N; Maruyama M; Nakajima Y
Journal:  RSC Adv       Date:  2020-10-13       Impact factor: 4.036

5.  Influence of surface charge of graphene quantum dots on their uptake and clearance in melanoma cells.

Authors:  Lakshmi Narashimhan Ramana; Le N M Dinh; Vipul Agarwal
Journal:  Nanoscale Adv       Date:  2021-04-15

6.  'Template-free' hierarchical MoS2 foam as a sustainable 'green' scavenger of heavy metals and bacteria in point of use water purification.

Authors:  Paresh Kumar Samantaray; Sushma Indrakumar; Kaushik Chatterjee; Vipul Agarwal; Suryasarathi Bose
Journal:  Nanoscale Adv       Date:  2020-05-06
  6 in total

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