M E Foeller1, S Zhao2, A Szabo2, M O Cruz1. 1. Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI, USA. 2. Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA.
Abstract
OBJECTIVE: To compare neonatal outcomes of twin pregnancies with gestational diabetes (GDM) and preexisting diabetes with non-diabetic twin pregnancies. STUDY DESIGN: US birth data from 2006 to 2009 was used to compare twin pregnancies of 16 562 GDM and 2137 preexisting diabetic with 258 857 non-diabetic twin gestations. Adjusted odds ratios (aORs) were calculated to assess effects of GDM and preexisting diabetes on neonatal outcomes. RESULT: Twin pregnancies with GDM vs non-diabetic twin pregnancies demonstrated decreased 5-min Apgar scores <4 (aOR 0.8, 95% confidence interval (CI) 0.68-0.94), fewer births before 32 weeks gestation (aOR 0.72, 95% CI 0.68-0.76), decreased birth weight less than the tenth percentile (aOR 0.84, 95% CI 0.81-0.89) and fifth percentile (aOR 0.85, 95% CI 0.81-0.89) and a trend toward lower rates of neonatal death (aOR 0.84, 95% CI 0.68-1.02). CONCLUSION: Certain adverse outcomes in pregnancies with GDM may be attenuated in twin gestations; however, further investigation is warranted.
OBJECTIVE: To compare neonatal outcomes of twin pregnancies with gestational diabetes (GDM) and preexisting diabetes with non-diabetic twin pregnancies. STUDY DESIGN: US birth data from 2006 to 2009 was used to compare twin pregnancies of 16 562 GDM and 2137 preexisting diabetic with 258 857 non-diabetic twin gestations. Adjusted odds ratios (aORs) were calculated to assess effects of GDM and preexisting diabetes on neonatal outcomes. RESULT: Twin pregnancies with GDM vs non-diabetic twin pregnancies demonstrated decreased 5-min Apgar scores <4 (aOR 0.8, 95% confidence interval (CI) 0.68-0.94), fewer births before 32 weeks gestation (aOR 0.72, 95% CI 0.68-0.76), decreased birth weight less than the tenth percentile (aOR 0.84, 95% CI 0.81-0.89) and fifth percentile (aOR 0.85, 95% CI 0.81-0.89) and a trend toward lower rates of neonatal death (aOR 0.84, 95% CI 0.68-1.02). CONCLUSION: Certain adverse outcomes in pregnancies with GDM may be attenuated in twin gestations; however, further investigation is warranted.
Authors: Nieves L González González; María Goya; Jordi Bellart; Jose Lopez; Maria A Sancho; Juan Mozas; Victoria Medina; Erika Padrón; Ana Megia; Pilar Pintado; Juan C Melchor; Gian C Di Renzo; José L Bartha Journal: J Matern Fetal Neonatal Med Date: 2011-11-01
Authors: Hye Jin Cho; Joong Sik Shin; Jae Hyug Yang; Hyun Mee Ryu; Moon Young Kim; Jung Yeol Han; Joo Oh Kim; Hyun Kyong Ahn; June Seek Choi; Jin Hoon Chung; Su Hyun Park; Min Hyoung Kim; Kyu Hong Choi Journal: J Korean Med Sci Date: 2006-06 Impact factor: 2.153