Literature DB >> 26509484

The Vascular Endothelium in Chronic Kidney Disease: A Novel Target for Aerobic Exercise.

Christopher R Martens1, Danielle L Kirkman, David G Edwards.   

Abstract

Endothelial dysfunction occurs in chronic kidney disease (CKD) and increases the risk for cardiovascular disease. The mechanisms of endothelial dysfunction seem to evolve throughout kidney disease progression, culminating in reduced L-arginine transport and impaired nitric oxide bioavailability in advanced disease. This review examines the hypothesis that aerobic exercise may reverse endothelial dysfunction by improving endothelial cell L-arginine uptake in CKD.

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Year:  2016        PMID: 26509484      PMCID: PMC5650477          DOI: 10.1249/JES.0000000000000065

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN: 0091-6331            Impact factor:   6.230


  41 in total

1.  Acute administration of L-arginine does not improve arterial endothelial function in chronic renal failure.

Authors:  J M Cross; A E Donald; R Kharbanda; J E Deanfield; R G Woolfson; R J MacAllister
Journal:  Kidney Int       Date:  2001-12       Impact factor: 10.612

2.  NADPH oxidase-derived reactive oxygen species contribute to impaired cutaneous microvascular function in chronic kidney disease.

Authors:  Jennifer J DuPont; Meghan G Ramick; William B Farquhar; Raymond R Townsend; David G Edwards
Journal:  Am J Physiol Renal Physiol       Date:  2014-04-23

3.  Effect of chronic renal failure on arginase and argininosuccinate synthetase expression.

Authors:  Hamid Moradi; Vincent Kwok; Nosratola D Vaziri
Journal:  Am J Nephrol       Date:  2006-06-29       Impact factor: 3.754

4.  Oral L-arginine improves endothelium-dependent dilation in hypercholesterolemic young adults.

Authors:  P Clarkson; M R Adams; A J Powe; A E Donald; R McCredie; J Robinson; S N McCarthy; A Keech; D S Celermajer; J E Deanfield
Journal:  J Clin Invest       Date:  1996-04-15       Impact factor: 14.808

5.  Effect of moderate-to-severe chronic kidney disease on flow-mediated dilation and progenitor cells.

Authors:  James M Kuczmarski; Mark D Darocki; Jennifer J DuPont; Robert A Sikes; Carlton R Cooper; William B Farquhar; David G Edwards
Journal:  Exp Biol Med (Maywood)       Date:  2011-07-26

6.  In vivo renal arginine release is impaired throughout development of chronic kidney disease.

Authors:  Gin-Fu Chen; Chris Baylis
Journal:  Am J Physiol Renal Physiol       Date:  2009-11-11

7.  Cardiac function is preserved following 4 weeks of voluntary wheel running in a rodent model of chronic kidney disease.

Authors:  James M Kuczmarski; Christopher R Martens; Jahyun Kim; Shannon L Lennon-Edwards; David G Edwards
Journal:  J Appl Physiol (1985)       Date:  2014-07-24

8.  Effect of exercise training on aortic tone in chronic renal insufficiency.

Authors:  Stan Shelkovnikov; Scott M Summers; Reza Elahimehr; Gregory Adams; Ralph E Purdy; Nosratola D Vaziri
Journal:  Am J Hypertens       Date:  2008-03-20       Impact factor: 2.689

9.  Physical functioning in patients with chronic kidney disease.

Authors:  J Padilla; J Krasnoff; M Da Silva; C-Y Hsu; L Frassetto; K L Johansen; P Painter
Journal:  J Nephrol       Date:  2008 Jul-Aug       Impact factor: 3.902

Review 10.  Exercise training in chronic kidney disease patients.

Authors:  Erin J Howden; Robert G Fassett; Nicole M Isbel; Jeff S Coombes
Journal:  Sports Med       Date:  2012-06-01       Impact factor: 11.136

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  15 in total

1.  Cerebral blood flow regulation in end-stage kidney disease.

Authors:  Justin D Sprick; Joe R Nocera; Ihab Hajjar; W Charles O'Neill; James Bailey; Jeanie Park
Journal:  Am J Physiol Renal Physiol       Date:  2020-09-28

Review 2.  Nutraceuticals as a potential adjunct therapy toward improving vascular health in CKD.

Authors:  Nicholas T Kruse
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-10-02       Impact factor: 3.619

3.  Effects of aerobic exercise on vascular function in nondialysis chronic kidney disease: a randomized controlled trial.

Authors:  Danielle L Kirkman; Meghan G Ramick; Bryce J Muth; Joseph M Stock; Ryan T Pohlig; Raymond R Townsend; David G Edwards
Journal:  Am J Physiol Renal Physiol       Date:  2019-02-27

4.  Aerobic Exercise Attenuates Kidney Injury, Improves Physical Performance, and Increases Antioxidant Defenses in Lungs of Adenine-Induced Chronic Kidney Disease Mice.

Authors:  Débora Melissa Petry Moecke; Gisele Henrique Cardoso Martins; Thaine Cristina Garlet; Kelly Cattelan Bonorino; Marilia Gabriela Luciani; Monique Bion; Barbara Dos Santos; Monique da Silva Gevaerd; Jamil Assreuy Filho; Adair Roberto Soares Dos Santos; Daniella Serafin Couto Vieira; Alcir Luiz Dafre; Deborah de Camargo Hizume Kunzler
Journal:  Inflammation       Date:  2022-06-21       Impact factor: 4.657

Review 5.  Nonepithelial mineralocorticoid receptor activation as a determinant of kidney disease.

Authors:  Toshifumi Nakamura; Sophie Girerd; Frederic Jaisser; Jonatan Barrera-Chimal
Journal:  Kidney Int Suppl (2011)       Date:  2022-03-18

6.  Role of mitochondria-derived reactive oxygen species in microvascular dysfunction in chronic kidney disease.

Authors:  Danielle L Kirkman; Bryce J Muth; Meghan G Ramick; Raymond R Townsend; David G Edwards
Journal:  Am J Physiol Renal Physiol       Date:  2017-11-08

7.  Aerobic Endurance Exercise Ameliorates Renal Vascular Sclerosis in Aged Mice by Regulating PI3K/AKT/mTOR Signaling Pathway.

Authors:  Chuncha Bao; Zhong Yang; Qian Li; Qiyan Cai; Hongli Li; Bin Shu
Journal:  DNA Cell Biol       Date:  2020-01-22       Impact factor: 3.311

Review 8.  Exercise intolerance in kidney diseases: physiological contributors and therapeutic strategies.

Authors:  Danielle L Kirkman; Natalie Bohmke; Salvatore Carbone; Ryan S Garten; Paula Rodriguez-Miguelez; Robert L Franco; Jason M Kidd; Antonio Abbate
Journal:  Am J Physiol Renal Physiol       Date:  2020-12-07

9.  Exercise plus caloric restriction lowers soluble RAGE in adults with chronic kidney disease.

Authors:  Steven K Malin; Sankar D Navaneethan; Ciaran E Fealy; Amanda Scelsi; Hazel Huang; Michael Rocco; John P Kirwan
Journal:  Obes Sci Pract       Date:  2020-02-11

Review 10.  The systemic role of SIRT1 in exercise mediated adaptation.

Authors:  Zsolt Radak; Katsuhiko Suzuki; Aniko Posa; Zita Petrovszky; Erika Koltai; Istvan Boldogh
Journal:  Redox Biol       Date:  2020-02-14       Impact factor: 11.799

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