Literature DB >> 26509312

Factors Predicting Testicular Atrophy after Testicular Salvage following Torsion.

Bertrand S Y Lian1, Caroline C P Ong2, Li Wei Chiang2, Rambha Rai2, Shireen Anne Nah2.   

Abstract

INTRODUCTION: Testicular atrophy (TA) is a significant complication in patients who undergo salvage procedures for testicular torsion. Studies on outcome focus on factors predicting testicular viability during scrotal exploration but few assess factors predicting TA in patients who undergo salvage procedures. We assess the incidence of TA after salvage and identify associated factors.
MATERIALS AND METHODS: With ethical approval, we reviewed patients who underwent salvage for testicular torsion in our institution from 2001 to 2013. Data was collected on patient demographics, duration of pain, sonographic findings, postoperative complications, and follow-up assessment of TA (defined as difference in testicular volume > 50% compared with the contralateral testis, based on measurement by Prader orchidometer or by ultrasound). We excluded patients with torted undescended testis, those under 1 month, and those with follow-up < 6 months. Chi-square or Mann-Whitney U tests were used as appropriate with significance level < 0.05.
RESULTS: Of 85 patients who had scrotal exploration for testicular torsion, 53 had testicular salvage. Overall, 16 patients defaulted or had < 6 months follow-up, leaving 37 patients who were studied, median age 12 years (range, 0.5-16.0 years) at presentation. Median follow-up was 12.5 months (range, 6-88 months). A total of 20 patients (54%) developed TA. Median duration to TA was 12.5 months (range, 2-88 months). All had clinical evidence of atrophy by 14 months, except two who initially defaulted follow-up, but were diagnosed with TA at 35 and 88 months postoperatively when presenting with unrelated complaints. Factors associated with TA were duration of pain > 1 day (p = 0.004) and heterogeneous echogenicity on ultrasound (p = 0.001). Sonographic evidence of reduced vascularity was not predictive. Of 11 that had pain > 1 day, 10 (91%) had TA. No testes survived when pain ≥ 3 days.
CONCLUSION: Half of patients with testicular torsion undergoing salvage surgery will develop testicular atrophy, even when intraoperatively assessed as viable, and should be counseled accordingly. Duration of pain > 1 day and sonographic heterogeneous echogenicity are predictive. Salvage rates are dismal when duration of symptoms exceeds 1 day. Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2015        PMID: 26509312     DOI: 10.1055/s-0035-1566096

Source DB:  PubMed          Journal:  Eur J Pediatr Surg        ISSN: 0939-7248            Impact factor:   2.191


  12 in total

1.  Does the source of referral affect outcomes for paediatric testicular torsion?

Authors:  R Peeraully; M Jancauskaite; S Dawes; S Green; N Fraser
Journal:  Ann R Coll Surg Engl       Date:  2019-06-03       Impact factor: 1.891

2.  Prospective Evaluation of Predictors of Testis Atrophy After Surgery for Testis Torsion in Children.

Authors:  Gwen M Grimsby; Bruce J Schlomer; Vani S Menon; Lauren Ostrov; Melise Keays; Kunj R Sheth; Carlos Villanueva; Candace Granberg; Daniel Dajusta; Martinez Hill; Emma Sanchez; Clanton B Harrison; Micah A Jacobs; Berk Burgu; Halim Hennes; Linda A Baker
Journal:  Urology       Date:  2018-03-20       Impact factor: 2.649

3.  Testicular salvage: using machine learning algorithm to develop a predictive model in testicular torsion.

Authors:  Mithat Ekşi; Abdullah Hizir Yavuzsan; İsmail Evren; Ali Ayten; Ali Emre Fakir; Fatih Akkaş; Kerem Bursali; Azad Akdağ; Selcuk Sahin; Ali İhsan Taşçi
Journal:  Pediatr Surg Int       Date:  2022-08-02       Impact factor: 2.003

4.  Degree of twisting and duration of symptoms are prognostic factors of testis salvage during episodes of testicular torsion.

Authors:  Adam S Howe; Vinaya Vasudevan; Michael Kongnyuy; Kevin Rychik; Lisa A Thomas; Maria Matuskova; Steven C Friedman; Jordan S Gitlin; Edward F Reda; Lane S Palmer
Journal:  Transl Androl Urol       Date:  2017-12

5.  Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats.

Authors:  Si-Ming Wei; Yu-Min Huang; Jian Zhou
Journal:  Oxid Med Cell Longev       Date:  2017-09-10       Impact factor: 6.543

Review 6.  The Impact of Testicular Torsion on Testicular Function.

Authors:  Frederik M Jacobsen; Trine M Rudlang; Mikkel Fode; Peter B Østergren; Jens Sønksen; Dana A Ohl; Christian Fuglesang S Jensen
Journal:  World J Mens Health       Date:  2019-04-10       Impact factor: 5.400

7.  Clinical evaluation of testicular torsion presenting with acute abdominal pain in young males.

Authors:  Fujun Wang; Zengnan Mo
Journal:  Asian J Urol       Date:  2018-05-26

8.  Risk Factors for Testicular Atrophy in Children With Testicular Torsion Following Emergent Orchiopexy.

Authors:  Xiao-Mao Tian; Xiao-Hui Tan; Qin-Lin Shi; Sheng Wen; Peng Lu; Xing Liu; Xu-Liang Li; Da-Wei He; Tao Lin; Guang-Hui Wei
Journal:  Front Pediatr       Date:  2020-11-11       Impact factor: 3.418

9.  Establishment and internal validation of preoperative nomograms for predicting the possibility of testicular salvage in patients with testicular torsion.

Authors:  Wan-Xiang Zheng; Guang-Dong Hou; Wei Zhang; Di Wei; Xue-Lin Gao; Mei-Hong Chen; Lu-Guang Huang; Fei Yan; Geng Zhang; Lei Yu; Fei Liu; Bo Zhang; Jian-Lin Yuan
Journal:  Asian J Androl       Date:  2021 Jan-Feb       Impact factor: 3.285

10.  Attenuation Effect of Salvianolic Acid B on Testicular Ischemia-Reperfusion Injury in Rats.

Authors:  Si-Ming Wei; Yu-Min Huang
Journal:  Oxid Med Cell Longev       Date:  2022-01-13       Impact factor: 6.543

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