Literature DB >> 26507909

Mass spectrometry-guided isolation of two new benzoquinoline alkaloids from Macleaya cordata.

Zhi-Xing Qing1,2, Yu-Qin Xu1, Peng Yang1,2, Kun Yu1,2, Pi Cheng3,2, Jian-Guo Zeng1,3,2.   

Abstract

Two new alkaloids, named 2,3-methylenedioxy-7,10-dimethyl-7,8,9,10-tetrahydro-benzoquinoline (1) and 2,3-methylenedioxy-7,10-dimethyl-8-carboxyl-benzoquinoline (2), were detected primarily from the fruits of Macleaya cordata by their different fragmentation pathways. And then isolation of the two compounds was performed by column chromatography and preparative HPLC under the guiding of mass spectrometry. Finally, their structures were determined by spectroscopic analysis.

Entities:  

Keywords:  2,3-methylenedioxy-7,10- dimethyl-7,8,9,10-tetrahydrobenzoquinoline; 2,3-methylenedioxy-7,10-dimethyl-8-carboxyl-benzoquinoline; Macleaya cordata; benzoquinoline alkaloids; mass spectrometry-guided isolation

Mesh:

Substances:

Year:  2015        PMID: 26507909     DOI: 10.1080/14786419.2015.1101695

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  4 in total

1.  Antidepressant-like activity, active components and related mechanism of Hemerocallis citrina Baroni extracts.

Authors:  Jinghong Liu; Tian Ye; Shuaiyong Yang; Xiaohong Zhong; Wei He; Mengtao Xu; Jinpeng Fang; Miao Deng; Ning Xu; Jianguo Zeng; Zhixing Qing
Journal:  Front Pharmacol       Date:  2022-08-29       Impact factor: 5.988

2.  Preclinical safety evaluation of Macleaya Cordata extract: A re-assessment of general toxicity and genotoxicity properties in rodents.

Authors:  Zhen Dong; Shu-Sheng Tang; Xiao-Lan Ma; Chang-Hong Li; Zhao-Shan Tang; Zi-Hui Yang; Jian-Guo Zeng
Journal:  Front Pharmacol       Date:  2022-08-12       Impact factor: 5.988

3.  Identification of the Impurities in Bopu Powder® and Sangrovit® by LC-MS Combined with a Screening Method.

Authors:  Zhuang Dong; Mengting Liu; Xiaohong Zhong; Xiaoyong Ou; Xuan Yun; Mingcan Wang; Shurui Ren; Zhixing Qing; Jianguo Zeng
Journal:  Molecules       Date:  2021-06-24       Impact factor: 4.411

4.  Systematic Detection and Identification of Bioactive Ingredients from Citrus aurantium L. var. amara Using HPLC-Q-TOF-MS Combined with a Screening Method.

Authors:  Liuyi Yu; Miaofen Chen; Jinghong Liu; Xiuqiong Huang; Wei He; Zhixing Qing; Jianguo Zeng
Journal:  Molecules       Date:  2020-01-15       Impact factor: 4.411

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.