Literature DB >> 26505064

Fluconazole exposure during pregnancy.

Yusuf Cem Kaplan, Gideon Koren, Pina Bozzo.   

Abstract

QUESTION: One of my patients has just learned that she is 8 weeks pregnant. She took a 150-mg dose of fluconazole 2 weeks ago for the treatment of vaginal candidiasis and she is worried about the effect on her child and pregnancy. Can I reassure her? ANSWER: Short-term and low-dose fluconazole exposure, such as that indicated in the treatment of vaginal candidiasis, is not expected to increase the overall risk of major congenital malformations.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 26505064      PMCID： PMC4541431     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  12 in total

1.  Pregnancy outcomes after maternal exposure to fluconazole.

Authors:  S S Jick
Journal:  Pharmacotherapy       Date:  1999-02       Impact factor: 4.705

2.  Multiple malformation syndrome following fluconazole use in pregnancy: report of an additional patient.

Authors:  K A Aleck; D L Bartley
Journal:  Am J Med Genet       Date:  1997-10-31

3.  Fluconazole treatment for vulvovaginal candidiasis during pregnancy.

Authors:  A Campomori; M Bonati
Journal:  Ann Pharmacother       Date:  1997-01       Impact factor: 3.154

4.  Prospective assessment of pregnancy outcomes after first-trimester exposure to fluconazole.

Authors:  P Mastroiacovo; T Mazzone; L D Botto; M A Serafini; A Finardi; L Caramelli; D Fusco
Journal:  Am J Obstet Gynecol       Date:  1996-12       Impact factor: 8.661

5.  Safety of fluconazole in the treatment of vaginal candidiasis. A prescription-event monitoring study, with special reference to the outcome of pregnancy.

Authors:  W Inman; G Pearce; L Wilton
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

6.  Fluconazole-induced congenital anomalies in three infants.

Authors:  T J Pursley; I K Blomquist; J Abraham; H F Andersen; J A Bartley
Journal:  Clin Infect Dis       Date:  1996-02       Impact factor: 9.079

7.  Maternal use of fluconazole and risk of congenital malformations: a Danish population-based cohort study.

Authors:  Mette Nørgaard; Lars Pedersen; Mette Gislum; Rune Erichsen; Kirstine Kobberøe Søgaard; Henrik Carl Schønheyder; Henrik Toft Sørensen
Journal:  J Antimicrob Chemother       Date:  2008-04-09       Impact factor: 5.790

8.  Congenital malformations in an infant born to a woman treated with fluconazole.

Authors:  B E Lee; M Feinberg; J J Abraham; A R Murthy
Journal:  Pediatr Infect Dis J       Date:  1992-12       Impact factor: 2.129

9.  Use of oral fluconazole during pregnancy and the risk of birth defects.

Authors:  Ditte Mølgaard-Nielsen; Björn Pasternak; Anders Hviid
Journal:  N Engl J Med       Date:  2013-08-29       Impact factor: 91.245

10.  The outcomes of pregnancy in women exposed to newly marketed drugs in general practice in England.

Authors:  L V Wilton; G L Pearce; R M Martin; F J Mackay; R D Mann
Journal:  Br J Obstet Gynaecol       Date:  1998-08
View more
  1 in total

1.  Guidelines to support HIV-affected individuals and couples to achieve pregnancy safely: Update 2018.

Authors:  Natasha E C G Davies; Gail Ashford; Linda-Gail Bekker; Nomathemba Chandiwana; Diane Cooper; Silker J Dyer; Lauren Jankelowitz; Otty Mhlongo; Coceka N Mnyani; Muhangwi B Mulaudzi; Michelle Moorhouse; Landon Myer; Malika Patel; Melanie Pleaner; Tatiana Ramos; Helen Rees; Sheree Schwartz; Jenni Smit; Doreen S van Zyl
Journal:  South Afr J HIV Med       Date:  2018-10-18       Impact factor: 2.744
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.