Literature DB >> 26503669

New formulation of old aspirin for better delivery.

Akil A Kalathil1, Anil Kumar1, Bhabatosh Banik1, Timothy A Ruiter1, Rakesh K Pathak1, Shanta Dhar1.   

Abstract

For better use of cyclooxygenase dependent anti-inflammatory properties and mitochondrial activities of aspirin, new hydrophobic analogues of aspirin were developed and successfully encapsulated in polymeric nanoparticles (NPs). In vivo anti-inflammatory effects of these NPs using a mouse model demonstrated unique properties of an optimized aspirin analogue to inhibit production of pro-inflammatory and enrichment of anti-inflammatory cytokines.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 26503669      PMCID： PMC4679634          DOI： 10.1039/c5cc07316b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  24 in total

Review 1.  Oxidative stress in neurodegeneration: cause or consequence?

Authors:  Julie K Andersen
Journal:  Nat Med       Date:  2004-07       Impact factor: 53.440

2.  A Nanoparticle Cocktail: Temporal Release of Predefined Drug Combinations.

Authors:  Rakesh K Pathak; Shanta Dhar
Journal:  J Am Chem Soc       Date:  2015-06-29       Impact factor: 15.419

3.  Variations in response to non-steroidal anti-inflammatory drugs.

Authors:  R O Day; P M Brooks
Journal:  Br J Clin Pharmacol       Date:  1987-06       Impact factor: 4.335

Review 4.  Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions.

Authors:  Anetta Undas; Kathleen E Brummel-Ziedins; Kenneth G Mann
Journal:  Blood       Date:  2006-12-05       Impact factor: 22.113

5.  Association of aspirin resistance with increased stroke severity and infarct size.

Authors:  Amy S Y Zheng; Leonid Churilov; Ruth E Colley; Christine Goh; Stephen M Davis; Bernard Yan
Journal:  JAMA Neurol       Date:  2013-02       Impact factor: 18.302

6.  Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics.

Authors:  Sean Marrache; Shanta Dhar
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-18       Impact factor: 11.205

Review 7.  Inflammation in neurodegenerative diseases.

Authors:  Sandra Amor; Fabiola Puentes; David Baker; Paul van der Valk
Journal:  Immunology       Date:  2010-02       Impact factor: 7.397

8.  Brain uptake of nonsteroidal anti-inflammatory drugs: ibuprofen, flurbiprofen, and indomethacin.

Authors:  Jagan Mohan R Parepally; Haritha Mandula; Quentin R Smith
Journal:  Pharm Res       Date:  2006-05-02       Impact factor: 4.200

9.  Evaluation of nanoparticle delivered cisplatin in beagles.

Authors:  Brittany Feldhaeusser; Simon R Platt; Sean Marrache; Nagesh Kolishetti; Rakesh K Pathak; David J Montgomery; Lisa R Reno; Elizabeth Howerth; Shanta Dhar
Journal:  Nanoscale       Date:  2015-09-07       Impact factor: 7.790

Review 10.  Engineered nanoparticles interacting with cells: size matters.

Authors:  Li Shang; Karin Nienhaus; Gerd Ulrich Nienhaus
Journal:  J Nanobiotechnology       Date:  2014-02-03       Impact factor: 10.435
View more
  10 in total

1.  Nanotechnology-mediated crossing of two impermeable membranes to modulate the stars of the neurovascular unit for neuroprotection.

Authors:  Bapurao Surnar; Uttara Basu; Bhabatosh Banik; Anis Ahmad; Brian Marples; Nagesh Kolishetti; Shanta Dhar
Journal:  Proc Natl Acad Sci U S A       Date:  2018-12-10       Impact factor: 11.205

2.  Mito-magneto: a tool for nanoparticle mediated mitochondria isolation.

Authors:  Bhabatosh Banik; Brett W Askins; Shanta Dhar
Journal:  Nanoscale       Date:  2016-12-01       Impact factor: 7.790

3.  Alleviating Aspirin-Induced Gastric Injury by Binding Aspirin to β-Lactoglobulin.

Authors:  Jin Chen; Min Gong; Zhuo Huang; Fang Wang; Yajing Wang; Zuquan Hu; Zhu Zeng; Yun Wang
Journal:  Drug Des Devel Ther       Date:  2022-03-01       Impact factor: 4.162

4.  Conjugates of urolithin A with NSAIDs, their stability, cytotoxicity, and anti-inflammatory potential.

Authors:  Maciej Korczak; Piotr Roszkowski; Sebastian Granica; Jakub P Piwowarski
Journal:  Sci Rep       Date:  2022-07-08       Impact factor: 4.996

5.  Centrifugation-Free Magnetic Isolation of Functional Mitochondria Using Paramagnetic Iron Oxide Nanoparticles.

Authors:  Bhabatosh Banik; Shanta Dhar
Journal:  Curr Protoc Cell Biol       Date:  2017-09-01

Review 6.  Nanotechnology inspired tools for mitochondrial dysfunction related diseases.

Authors:  Ru Wen; Bhabatosh Banik; Rakesh K Pathak; Anil Kumar; Nagesh Kolishetti; Shanta Dhar
Journal:  Adv Drug Deliv Rev       Date:  2016-01-09       Impact factor: 15.470

7.  Rational Design 2-Hydroxypropylphosphonium Salts as Cancer Cell Mitochondria-Targeted Vectors: Synthesis, Structure, and Biological Properties.

Authors:  Vladimir F Mironov; Andrey V Nemtarev; Olga V Tsepaeva; Mudaris N Dimukhametov; Igor A Litvinov; Alexandra D Voloshina; Tatiana N Pashirova; Eugenii A Titov; Anna P Lyubina; Syumbelya K Amerhanova; Aidar T Gubaidullin; Daut R Islamov
Journal:  Molecules       Date:  2021-10-20       Impact factor: 4.411

8.  Strong and Long-Lasting Antinociceptive and Anti-inflammatory Conjugate of Naturally Occurring Oleanolic Acid and Aspirin.

Authors:  Barbara Bednarczyk-Cwynar; Natalia Wachowiak; Michal Szulc; Ewa Kamińska; Anna Bogacz; Joanna Bartkowiak-Wieczorek; Lucjusz Zaprutko; Przemyslaw L Mikolajczak
Journal:  Front Pharmacol       Date:  2016-07-12       Impact factor: 5.810

Review 9.  Mitochondrion: A Promising Target for Nanoparticle-Based Vaccine Delivery Systems.

Authors:  Ru Wen; Afoma C Umeano; Lily Francis; Nivita Sharma; Smanla Tundup; Shanta Dhar
Journal:  Vaccines (Basel)       Date:  2016-06-01

10.  Turn up the cellular power generator with vitamin E analogue formulation.

Authors:  Ru Wen; Shanta Dhar
Journal:  Chem Sci       Date:  2016-05-09       Impact factor: 9.825
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.