Literature DB >> 26502854

The role of eosinophils in stroke: a pilot study.

L-B Guo1, S Liu, F Zhang, G-S Mao, L-Z Sun, Y Liu.   

Abstract

OBJECTIVE: To evaluate the factors that may have an impact on the prognosis of ischemic stroke. PATIENTS AND METHODS: The study included 973 patients who were diagnosed with an ischemic stroke. The patients were divided into 6 groups according their eosinophil counts' level and occurred times. All patients were supervised by NIHSS score in three months.
RESULTS: Baseline characteristics of all study groups were comparable. Thirty-four patients in group 2 and group 5 had higher eosinophil counts. In addition, the patients experienced impaired function on the face, but no impairment of limbs. All patients in these groups recovered quicker than the other groups (p < 0.05). Furthermore, 169 patients in both group 3 and group 6 had lower eosinophil counts. These patients experienced functional impairment in limbs and difficulty recovering from the disease. The NIHSS score was lower in both group 2 and group 5, compared with group 3 and group 6 (p < 0.05).
CONCLUSIONS: This study suggests that eosinophil counts may have a significant impact on outcomes in stroke patients. The data underscore the importance in further investigating eosinophil dysregulation as well as the potential relationship between eosinophil dysregulation and organ functions in stroke patients.

Entities:  

Mesh:

Year:  2015        PMID: 26502854

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  7 in total

1.  Cortisol is More Important than Metanephrines in Driving Changes in Leukocyte Counts after Stroke.

Authors:  Dannielle Zierath; Patricia Tanzi; Dean Shibata; Kyra J Becker
Journal:  J Stroke Cerebrovasc Dis       Date:  2017-10-31       Impact factor: 2.136

2.  Eosinophils, Stroke-Associated Pneumonia, and Outcome After Mechanical Thrombectomy for Acute Ischemic Stroke.

Authors:  Zhiliang Guo; Jie Hou; Shuai Yu; Hang Zhang; Shuhong Yu; Huaishun Wang; Jiaping Xu; Shoujiang You; Zhichao Huang; Guodong Xiao; Yongjun Cao; Chun-Feng Liu
Journal:  Front Aging Neurosci       Date:  2022-05-23       Impact factor: 5.702

Review 3.  Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art.

Authors:  Marialuisa Gandolfi; Nicola Smania; Antonio Vella; Alessandro Picelli; Salvatore Chirumbolo
Journal:  Neural Plast       Date:  2017-03-08       Impact factor: 3.599

4.  Absolute blood eosinophil count could be a potential biomarker for predicting haemorrhagic transformation after intravenous thrombolysis for acute ischaemic stroke.

Authors:  Neringa Jucevičiūtė; Paulius Mikužis; Renata Balnytė
Journal:  BMC Neurol       Date:  2019-06-13       Impact factor: 2.474

Review 5.  Cellular and Molecular Mechanisms of R/S-Roscovitine and CDKs Related Inhibition under Both Focal and Global Cerebral Ischemia: A Focus on Neurovascular Unit and Immune Cells.

Authors:  Lucas Le Roy; Anne Letondor; Cloé Le Roux; Ahmed Amara; Serge Timsit
Journal:  Cells       Date:  2021-01-08       Impact factor: 6.600

6.  Leukocyte subtypes and adverse clinical outcomes in patients with acute ischemic cerebrovascular events.

Authors:  Anxin Wang; Kehua Quan; Xue Tian; Yingting Zuo; Xia Meng; Pan Chen; Hao Li; Yongjun Wang
Journal:  Ann Transl Med       Date:  2021-05

7.  Eosinophil-to-Neutrophil Ratio Predicts Poor Prognosis of Acute Ischemic Stroke Patients Treated With Intravenous Thrombolysis.

Authors:  Haoye Cai; Honghao Huang; Chenguang Yang; Junli Ren; Jianing Wang; Beibei Gao; Wenjing Pan; Fangyue Sun; Xinbo Zhou; Tian Zeng; Jingyu Hu; Yilin Chen; Shunkai Zhang; Guangyong Chen
Journal:  Front Neurol       Date:  2021-07-12       Impact factor: 4.003

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.