Literature DB >> 26500116

Glucagon Is a Safe and Inexpensive Initial Strategy in Esophageal Food Bolus Impaction.

Jason Haas1,2, Julia Leo3, Nimish Vakil4,5,6.   

Abstract

BACKGROUND: Controversy exists about the utility of pharmacologic agents and endoscopic technique used for esophageal food bolus impaction. AIM: To evaluate the utility of glucagon and the technique used for endoscopic removal, including the rate of success and the adverse events of the techniques.
METHODS: The database of the largest healthcare provider in southeastern Wisconsin was retrospectively reviewed for patients presenting with esophageal food bolus impaction. Data extracted included glucagon administration and its success rate, outcome of radiographic studies, and the endoscopic method of removal and adverse events associated with it, including 30-day mortality.
RESULTS: A total of 750 patients were identified with food bolus impaction from 2007 to 2012. Glucagon was administered in 440 patients and was successful in 174 (39.5%). Endoscopic removal was performed in 470 patients and was successful in 469 (99.8%). The push technique was utilized in 209 patients, reduction in the bolus size by piecemeal removal followed by the push technique was utilized in 97 patients, and the pull technique was utilized in 107 patients. There were no perforations with endoscopic removal. Only 4.5% of the X-rays performed reported a possible foreign body within the esophagus. Glucagon was a significantly less-expensive strategy than endoscopic therapy (p < 0.0001).
CONCLUSION: Glucagon is low cost, is moderately effective, and may be considered as an initial strategy. Endoscopic removal regardless of technique is safe and effective. The yield of radiography is poor in the setting of food bolus impaction.

Entities:  

Keywords:  Dysphagia; Endoscopy; Food bolus impaction; Foreign body; Glucagon

Mesh:

Substances:

Year:  2015        PMID: 26500116     DOI: 10.1007/s10620-015-3934-z

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  9 in total

1.  Assessment of the predictors of response to glucagon in the setting of acute esophageal food bolus impaction.

Authors:  Thomas C Sodeman; Gavin C Harewood; Todd H Baron
Journal:  Dysphagia       Date:  2004       Impact factor: 3.438

Review 2.  Myth: glucagon is an effective first-line therapy for esophageal foreign body impaction.

Authors:  Sanjay Arora; Peter Galich
Journal:  CJEM       Date:  2009-03       Impact factor: 2.410

3.  Management of ingested foreign bodies and food impactions.

Authors:  Steven O Ikenberry; Terry L Jue; Michelle A Anderson; Vasundhara Appalaneni; Subhas Banerjee; Tamir Ben-Menachem; G Anton Decker; Robert D Fanelli; Laurel R Fisher; Norio Fukami; M Edwyn Harrison; Rajeev Jain; Khalid M Khan; Mary Lee Krinsky; John T Maple; Ravi Sharaf; Laura Strohmeyer; Jason A Dominitz
Journal:  Gastrointest Endosc       Date:  2011-06       Impact factor: 9.427

4.  Association of eosinophilic inflammation with esophageal food impaction in adults.

Authors:  Tusar K Desai; Veslav Stecevic; Chung-Ho Chang; Neal S Goldstein; Kamran Badizadegan; Glenn T Furuta
Journal:  Gastrointest Endosc       Date:  2005-06       Impact factor: 9.427

Review 5.  Endoscopic management of foreign bodies in the upper gastrointestinal tract: A review.

Authors:  Choichi Sugawa; Hiromi Ono; Mona Taleb; Charles E Lucas
Journal:  World J Gastrointest Endosc       Date:  2014-10-16

6.  Effect of doses of glucagon used to treat food impaction on esophageal motor function of normal subjects.

Authors:  V Colon; A Grade; G Pulliam; C Johnson; R Fass
Journal:  Dysphagia       Date:  1999       Impact factor: 3.438

7.  Use of glucagon in relieving esophageal food bolus impaction in the era of eosinophilic esophageal infiltration.

Authors:  Jayaram Thimmapuram; Scott Oosterveen; Rodney Grim
Journal:  Dysphagia       Date:  2012-12-01       Impact factor: 3.438

8.  Treatment of acute esophageal food impaction with glucagon, an effervescent agent, and water.

Authors:  M I Robbins; M J Shortsleeve
Journal:  AJR Am J Roentgenol       Date:  1994-02       Impact factor: 3.959

9.  Effect of spasmolytic drugs on esophageal foreign bodies.

Authors:  L Tibbling; A Bjorkhoel; E Jansson; M Stenkvist
Journal:  Dysphagia       Date:  1995       Impact factor: 3.438

  9 in total
  3 in total

1.  The evolution of treatment and complications of esophageal food impaction.

Authors:  Daniel A Schupack; Charles J Lenz; Debra M Geno; Crystal J Tholen; Cadman L Leggett; David A Katzka; Jeffrey A Alexander
Journal:  United European Gastroenterol J       Date:  2019-03-05       Impact factor: 4.623

2.  Flexible versus rigid endoscopy in the management of esophageal foreign body impaction: systematic review and meta-analysis.

Authors:  Davide Ferrari; Alberto Aiolfi; Gianluca Bonitta; Carlo Galdino Riva; Emanuele Rausa; Stefano Siboni; Francesco Toti; Luigi Bonavina
Journal:  World J Emerg Surg       Date:  2018-09-12       Impact factor: 5.469

3.  Cola therapy for oesophageal food bolus impactions a case series.

Authors:  Eva P Baerends; Tom Boeije; Anna Van Capelle; Nieke E Mullaart-Jansen; Michael D Burg; Albert J Bredenoord
Journal:  Afr J Emerg Med       Date:  2018-10-13
  3 in total

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