| Literature DB >> 26498583 |
Abstract
Multiple treatment options are available for patients who have peripheral nerve injuries with a gap. Decellular nerve allografts are one option and provide an extracellular scaffold for neuronal cells to migrate for axonal regrowth. Immunosuppression is not needed because improved nerve processing technologies have rendered decellular nerve allografts nonimmunogenic. These allografts have also shown promising results in both animal and human studies as an alternative repair option. Copyright 2015 by the American Academy of Orthopaedic Surgeons.Entities:
Keywords: Peripheral nerve injury; acellular nerve allograft; decellular nerve allograft; regeneration; repair
Mesh:
Year: 2015 PMID: 26498583 DOI: 10.5435/JAAOS-D-14-00373
Source DB: PubMed Journal: J Am Acad Orthop Surg ISSN: 1067-151X Impact factor: 3.020