Literature DB >> 26498488

Antidiabetic and Antihyperlipidemic Effects of Ethanol Extract of Rosa canina L. fruit on Diabetic Rats: An Experimental Study With Histopathological Evaluations.

Mohsen Taghizadeh1, Ali Akbar Rashidi2, Ali Akbar Taherian3, Zarichehr Vakili1, Mohammad Sajad Sajadian1, Mostafa Ghardashi1.   

Abstract

Rosa canina L. (Rosaceae) has been traditionally used as a medicinal plant. This study was undertaken to evaluate the antidiabetic and antihyperlipidemic effects of Rosa canina fruit extract in streptozotocin induced diabetic rats. The results showed oral administration of Rosa canina fruit extract significantly ameliorated the high levels of blood glucose compared with the control group. Serum triglyceride levels significantly decreased by the administration of Rosa canina extract compared with control. Histopathological examinations showed that the Rosa canina extract improved islets necrotic and regenerated pancreatic islet cells. Rosa canina extract has the antihyperglycemic and antihyperlipidemic effects in streptozotocin-induced diabetic rats.
© The Author(s) 2015.

Entities:  

Keywords:  diabetes mellitus; hyperglycemia; lipids; medicinal plants

Mesh：

Substances：

Year:  2015        PMID： 26498488     DOI： 10.1177/2156587215612626

Source DB:  PubMed          Journal:  J Evid Based Complementary Altern Med        ISSN： 2156-5899


  8 in total

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Review 3.  Therapeutic Applications of Rose Hips from Different Rosa Species.

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Review 5.  Chemical constituents and pharmacological activities of medicinal plants from Rosa genus.

Authors:  Yansheng Wang; Yanmin Zhao; Xinnan Liu; Jingyang Li; Jingze Zhang; Dailin Liu
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6.  Optimized Ultrasound-Assisted Enzymatic Extraction of Phenolic Compounds from Rosa canina L. Pseudo-Fruits (Rosehip) and Their Biological Activity.

Authors:  Alexandru Nicolescu; Mihai Babotă; Leilei Zhang; Claudiu I Bunea; Laura Gavrilaș; Dan C Vodnar; Andrei Mocan; Gianina Crișan; Gabriele Rocchetti
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7.  Probiotic fruit beverages with different polyphenol profiles attenuated early insulin response.

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8.  Molecular mechanism of the anti-diabetic activity of an identified oligosaccharide from Rosa canina.

Authors:  Gholamreza Bahrami; Seyed Shahram Miraghaee; Bahar Mohammadi; Mohammad Taher Bahrami; Gholamreza Taheripak; Samira Keshavarzi; Atefeh Babaei; Soraya Sajadimajd; Razieh Hatami
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  8 in total

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